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Glossary

AbdomenThe portion of the trunk between the diaphragm and pelvis.
AbductionThe movement of a body part away from the axis or midline of the body; movement of a digit away from the axis of the limb.
ABO systemThe most common system of classification for red blood cell antigens. On the basis of antigens on the red blood cell surface, individuals can be type A, type B, type AB, or type O.
AbsorptionThe transport of molecules across epithelial membranes into the body fluids.
Accessory organsOrgans that assist with the functioning of other organs within a system.
AccommodationA process whereby the focal length of the eye is changed by automatic adjustment of the curvature of the lens to bring images of objects from various distances into focus on the retina.
AcetabulumA socket in the lateral surface of the hipbone (os coxa) with which the head of the femur articulates.
AcetoneA ketone body produced as a result of the oxidation of fats.
Acetyl coenzyme AA coenzyme derivative in the metabolism of glucose and fatty acids that contributes substrates to the Krebs cycle.
Acetylcholine (ACh)An acetic acid ester of choline-a substance that functions as a neurotransmitter in somatic motor nerve and parasympathetic nerve fibers.
AcetylcholinesteraseAn enzyme in the membrane of postsynaptic cells that catalyzes the conversion of ACh into choline and acetic acid. This enzymatic reaction inactivates the neurotransmitter.
Achilles tendonSee tendo calcaneous.
AcidA substance that releases hydrogen ions when ionized in water.
AcidosisAn abnormal increase in the H+ concentration of the blood that lowers the arterial pH to below 7.35.
AcromegalyA condition caused by the hypersecretion of growth hormone from the pituitary gland after maturity and characterized by enlargement of the extremities, such as the nose, jaws, fingers, and toes.
ActinA protein in muscle fibers that together with myosin is responsible for contraction.
Action potentialAn all-or-none electrical event in an axon or muscle fiber in which the polarity of the membrane potential is rapidly reversed and re-established.
Active immunityImmunity involving sensitization, in which antibody production is stimulated by prior exposure to an antigen.
Active transportThe movement of molecules or ions across the cell membranes of epithelial cells by membrane carriers. An expenditure of cellular energy (ATP) is required.
AdductionThe movement of a body part toward the axis or midline of the body; movement of a digit toward the axis of the limb.
AdenohypophysisThe anterior, glandular lobe of the pituitary gland that secretes FSH (follicle-stimulating hormone), LH (luteinizing hormone), ACTH (adrenocorticotropic hormone), TSH (thyroid-stimulating hormone), GH (growth hormone), and prolactin. Secretions of the adenohypophysis are controlled by hormones produced by the hypothalamus.
AdenoidsThe tonsils located in the nasopharynx; pharyngeal tonsils.
Adenylate cyclaseAn enzyme found in cell membranes that catalyses the conversion of ATP to cyclic AMP and pyrophosphate (PP1). This enzyme is activated by an interaction between a specific hormone and its membrane receptor protein.
ADHAntidiuretic hormone; a hormone produced by the hypothalamus and released by the posterior pituitary that acts on the kidneys to promote water reabsorption; also known as vasopressin.
ADPAdenosine diphosphate; a molecule that together with inorganic phosphate is used to make ATP (adenosine triphosphate).
Adrenal cortexThe outer part of the adrenal gland. Derived from embryonic mesoderm, the adrenal cortex secretes corticosteroid hormones (such as aldosterone and hydrocortisone).
Adrenal medullaThe inner part of the adrenal gland. Derived from embryonic postganglionic sympathetic neurons, the adrenal medulla secretes catecholamine hormones-epinephrine and (to a lesser degree) norepinephrine.
AdrenergicA term used to describe the actions of epinephrine, norepinephrine, or other molecules with similar activity (as in adrenergic receptor and adrenergic stimulation).
AdventitiaThe outermost epithelial layer of a visceral organ; also called serosa.
AfferentConveying or transmitting to.
Afferent arterioleA blood vessel within the kidney that supplies blood to the glomerulus.
Afferent neuronSee sensory neuron.
AgglutinateA clump of cells (usually erythrocytes) formed as a result of specific chemical interaction between surface antigens and antibodies.
Agranular leukocytesWhite blood cells (leukocytes) that do not contain cytoplasmic granules; specifically, lymphocytes and monocytes.
AlbuminA water-soluble protein produced in the liver; the major component of the plasma proteins.
AldosteroneThe principal corticosteroid hormone involved in the regulation of electrolyte balance (mineralocorticoid).
Alimentary canalThe tubular portion of the digestive tract. See also gastrointestinal tract (GI tract).
AllantoisAn extraembryonic membranous sac involved in the formation of blood cells. It gives rise to the fetal umbilical arteries and vein and also contributes to the formation of the urinary bladder.
AllergensAntigens that evoke an allergic response rather than a normal immune response.
AllergyA state of hypersensitivity caused by exposure to allergens. It results in the liberation of histamine and other molecules with histamine like effects.
All-or-none principleThe statement of the fact that muscle fibers of a motor unit contract to their maximum extent when exposed to a stimulus of threshold strength.
AllostericA term used with reference to the alteration of an enzyme's activity as a result of its combination with a regulator molecule. Allosteric inhibition by an end product represents negative feedback control of an enzyme's activity.
Alveolar sacsA cluster of alveoli that share a common chamber or central atrium.
Alveolus1.An individual air capsule within the lung. The alveoli are the basic functional units of respiration. 2.The socket that secures a tooth(tooth socket).
AmniocentesisA procedure in which a sample of amniotic fluid is aspirated to examine suspended cells for various genetic diseases.
AmnionA developmental membrane surrounding the fetus that contains amniotic fluid.
AmphiarthrosisA slightly movable articulation in a functional classification of joints.
AmphotericHaving both acidic and basic characteristics; used to denote a molecule that can be positively or negatively charged, depending on the pH of its environment.
AmpullaA saclike enlargement of a duct or tube.
Ampulla of VaterSee hepatopancreatic ampulla.
Anabolic steroidsSteroids with androgen like stimulatory effects on protein synthesis.
AnabolismA phase of metabolism involving chemical reactions within cells that result in the production of larger molecules from smaller ones; specifically, the synthesis of protein, glycogen, and fat.
Anaerobic respirationA form of cell respiration involving the conversion of glucose to lactic acid in which energy is obtained without the use of molecular oxygen.
Anal canalThe terminal tubular portion of the large intestine that opens through the anus of the GI tract.
AnaphylaxisAn unusually severe allergic reaction that can result in cardiovascular shock and death.
AnastomosisAn interconnecting aggregation of blood vessels or nerves that form a network plexus.
Anatomical positionAn erect body stance with the eyes directed interior, the arms at the sides, the palms of the hands facing interior, and the fingers pointing straight down.
AnatomyThe branch of science concerned with the structure of the body and the relationship of its organs.
AndrogensSteroids containing 18 carbons that have masculinizing effects; primarily those hormones (such as testosterone) secreted by the testes, although weaker androgens are also secreted by the adrenal cortex.
AnemiaAn abnormal reduction in the red blood cell count, hemoglobin concentration, or hematocrit, or any combination of these measurements. This condition is associated with a decreased ability of the blood to carry oxygen.
Angina pectorisA thoracic pain, often referred to the left pectoral and arm area, caused by myocardial ischemia.
Angiotensin IIAn 8-amino-acid polypeptide formed from angiotensin I(a 10-amino-acid precursor), which in turn is formed from cleavage of a protein(angiotensinogen) by the action of renin(an enzyme secreted by the kidneys). Angiotensin II is a powerful vasoconstrictor and a stimulator of aldosterone secretion from the adrenal cortex.
AnionsIons that are negatively charged, such as chloride, bicarbonate, and phosphate.
AntagonistA muscle that acts in opposition to another muscle.
AntebrachiumThe forearm.
AnteriorToward the front; the opposite of posterior, or dorsal.
Anterior pituitarySee adenohypophysis.
Anterior rootThe anterior projection of the spinal cord, composed of axons of motor neurons.
AntibodiesImmunoglobin proteins secreted by B lymphocytes that have transformed into plasma cells. Antibodies are responsible for humoral immunity. Their synthesis is induced by specific antigens, and they combine with these specific antigens but not with unrelated antigens.
AnticodonA base triplet provided by three nucleotides within a loop of transfer RNA that is complementary in its base-pairing properties to a triplet (the codon) in mRNA. The matching of codon to anticodon provides the mechanism for translating the genetic code into a specific sequence of amino acids.
AntigenA molecule that can induce the production of antibodies and react in a specific manner with antibodies.
Antigenic determinant siteThe region of an antigen molecule that specifically reacts with particular antibodies. A large antigen molecule may have a number of such sites.
AntiserumA serum that contains specific antibodies.
AnusThe terminal opening of the GI tract.
AortaThe major systemic vessel of the arterial system of the body, emerging from the left ventricle.
Aortic archThe superior left bend of the aorta between the ascending and descending portions.
ApexThe tip or pointed end of a conical structure.
AphasiaDefects in speech, writing, or in the comprehension of spoken or written language caused by brain damage or disease.
Apneustic centerA collection of nuclei(nerve cell bodies) in the brain stem that participates in the rhythmic control of breathing.
Apocrine glandA type of sweat gland that functions in evaporative cooling. It may respond during periods of emotional stress.
AponeurosisA fibrous or membranous sheet like tendon.
AppendixA short pouch that attaches to the cecum.
Aqueous humorThe watery fluid that fills the anterior and posterior chambers of the eye.
Arachnoid materThe weblike middle covering(meninx) of the central nervous system.
Arbor vitaeThe branching arrangement of white matter within the cerebellum.
ArmThe portion of the upper extremity from the shoulder to the elbow.
Arrector pili muscleThe smooth muscle attached to a hair follicle that, upon contraction, pulls the hair into a more vertical position, resulting in "goose bumps."
ArterioleA minute arterial branch.
ArteriosclerosisAny one of a group of diseases characterized by thickening and hardening of the artery wall and in the narrowing of its lumen.
Arteriovenous anastomosesDirect connections between arteries and veins that bypass capillary beds.
ArteryA blood vessel that carries blood away from the heart.
ArthrologyThe scientific study of the structure and function of joints.
Articular cartilageA hyaline cartilaginous covering over the articulating surface of the bones of synovial joints.
ArticulationA joint.
Arytenoid cartilagesA pair of small cartilages located on the superior aspect of the larynx.
Ascending colonThe portion of the large intestine between the cecum and the hepatic flexure.
Association neuronA nerve cell located completely within the central nervous system. It conveys impulses in an arc from sensory to motor neurons; also called interneuron or internuncial neuron.
AstigmatismUnequal curvature of the refractive surfaces of the eye (cornea and/or lens), so that light entering the eye along certain meridians does not focus on the retina.
AtherosclerosisA common type of arteriosclerosis found in medium and larger arteries in which raised areas within the tunica intima are formed from smooth muscle cells, cholesterol, and other lipids. These plaques occlude arteries and serve as sites for the formation of thrombi.
Atomic numberThe number of protons in the nucleus of an atom.
Atopic dermatitisAn allergic skin reaction to agents such as poison ivy and poison oak; a type of delayed hypersensitivity.
ATPAdenosine triphosphate; the universal energy donor of the cell.
AtreticWithout an opening. Atretic ovarian follicles are those that fail to ovulate.
Atrioventricular bundleA group of specialized cardiac fibers that conduct impulses from the atrioventricular node to the ventricular muscles of the heart; also called the bundle of His or AV bundle.
Atrioventricular nodeA microscopic aggregation of specialized cardiac fibers located in the interatrial septum of the heart that are a part of the conduction system of the heart; AV node.
Atrioventricular valveA cardiac valve located between an atrium and a ventricle of the heart; AV valve.
AtriumEither of the two superior chambers of the heart that receive venous blood.
AtrophyA gradual wasting away or decrease in the size of a tissue or an organ.
AtropineAn alkaloid drug obtained from a plant of the species Belladonna that acts as an anticholinergic agent. It is used medically to inhibit parasympathetic nerve effects, dilate the pupils of the eye, increase the heart rate, and inhibit intestinal movements.
AuditoryPertaining to the structures of the ear associated with hearing.
Auditory tubeA narrow canal that connects the middle ear chamber to the pharynx; also called the eustachian canal.
Auricle1.The fleshy pinna of the ear. 2.An ear-shaped appendage of each atrium of the heart.
AutoantibodiesAntibodies formed in response to, and that react with, molecules that are part of one's own body.
Autonomic nervous systemThe sympathetic and parasympathetic portions of the nervous system that function to control the actions of the visceral organs and skin; ANS.
Autosomal chromosomesThe paired chromosomes; those other than the sex chromosomes.
AxillaThe depressed hollow commonly called the armpit.
AxonThe elongated process of a nerve cell that transmits an impulse away from the cell body of a neuron.
BasophilA granular leukocyte that readily stains with basophilic dye.
B cell lymphocytesLymphocytes that can be transformed by antigens into plasma cells that secrete antibodies (and are thus responsible for humoral immunity). The B stands for bursa equivalent.
BellyThe thickest circumference of a skeletal muscle.
BenignNot malignant.
BifurcateForked; divided into two branches.
BileA liver secretion that is stored and concentrated in the gallbladder and released through the common bile duct into the duodenum. It is essential for the absorption of fats.
BilirubinBile pigment derived from the breakdown of the heme portion of hemoglobin.
BipennateDenoting muscles that have a fibre architecture coursing obliquely on both sides of a tendon.
BlastulaAn early stage of prenatal development between the morula and embryonic period.
BloodThe fluid connective tissue that circulates through the cardiovascular system to transport substances throughout the body.
Blood-brain barrierA specialized mechanism that inhibits the passage of certain materials from the blood into brain tissue and cerebrospinal fluid.
BolusA moistened mass of food that is swallowed from the oral cavity into the pharynx.
BoneA solid, rigid, ossified connective tissue forming an organ of the skeletal system.
Bony labyrinthA series of chambers within the petrous part of the temporal bone associated with the vestibular organs and the cochlea. The bony labyrinth contains a fluid called perilymph.
Bowman's capsuleSee glomerular capsule.
Brachial plexusA network of nerve fibers that arise from spinal nerves C5-C8 and T1. Nerves arising from the brachial plexuses supply the upper extremities.
BradycardiaA slow cardiac rate; fewer than 60 beats per minute.
BradykininsShort polypeptides that stimulate vasodilation and other cardiovascular changes.
BrainThe enlarged superior portion of the central nervous system located in the cranial cavity of the skull.
Brain stemThe portion of the brain consisting of the medulla oblongata, pons, and midbrain.
Bronchial treeThe bronchi and their branching bronchioles.
BronchioleA small division of a bronchus within the lung.
BronchusA branch of the trachea that leads to a lung.
Buccal cavityThe mouth, or oral cavity.
BufferA molecule that serves to prevent large changes in pH by either combining with H+ or by releasing H+ into solution.
Bulbourethral glandsA pair of glands that secrete a viscous fluid into the male urethra during sexual excitement; also called Cowper's glands. bundle of His See atrioventricular bundle.
BursaA saclike structure filled with synovial fluid. Bursae are located at friction points, as around joints, over which tendons can slide without contacting bone.
ButtocksThe rump or fleshy masses on the posterior aspect of the lower trunk, formed primarily by the gluteal muscles.
CalcitoninAlso called thyrocalcitonin. A polypeptide hormone produced by the parafollicular cells of the thyroid and secreted in response to hypercalcemia. It acts to lower blood calcium and phosphate concentrations and may serve as an antagonist of parathyroid hormones.
CalmodulinA receptor protein for Ca++ located within the cytoplasm of target cells. It appears to mediate the effects of this ion on cellular activities.
CalorieA unit of heat equal to the amount needed to raise the temperature of one gram of water by 1 C∞.
CalyxA cup-shaped portion of the renal pelvis that encircles a renal papilla.
CanaliculusA microscopic channel in bone tissue that connects lacunae.
Canal of SchlemmSee scleral venous sinus.
CancerA tumour characterized by abnormally rapid cell division and the loss of specialized tissue characteristics. This term usually refers to malignant tumours.
CapacitationThe process whereby spermatozoa gain the ability to fertilize ova. Sperm that have not have been capacitated in the female reproductive tract cannot fertilize ova.
CapillaryA microscopic blood vessel that connects an arteriole and a venule; the functional unit of the circulatory system.
Carbonic anhydraseAn enzyme that catalyses the formation or breakdown of carbonic acid. When carbon dioxide concentrations are relatively high, this enzyme catalyses the formation of carbonic acid from CO2 and H2O. When carbon dioxide concentrations are low, the breakdown of carbonic acid to CO2 and H2O is catalysed. These reactions aid the transport of carbon dioxide from tissues to alveolar air.
Cardiac muscleMuscle of the heart, consisting of striated muscle cells. These cells are interconnected into a mass called the myocardium.
Cardiac outputThe volume of blood pumped per minute by either the right or left ventricle.
Cardiogenic shockShock that results from low cardiac output in heart disease.
Carotid sinusAn expanded portion of the internal carotid artery located immediately above the point of branching from the external carotid artery. The carotid sinus contains baroreceptors that monitor blood pressure.
CarpusThe proximal portion of the hand that contains the eight carpal bones.
Carrier-mediated transportThe transport of molecules or ions across a cell membrane by means of specific protein carriers. It includes both facilitated diffusion and active transport.
CartilageA type of connective tissue with a solid elastic matrix.
Cartilaginous jointA joint that lacks a joint cavity, permitting little movement between the bones held together by cartilage.
CastAn accumulation of proteins molded from the kidney tubules that appears in urine sediment
CatabolismThe metabolic breakdown of complex molecules into simpler ones, often resulting in a release of energy.
CatecholaminesA group of molecules including epinephrine, norepinephrine, L-dopa, and related molecules with effects similar to those produced by activation of the sympathetic nervous system.
CationsPositively charged ions, such as sodium, potassium, calcium, and magnesium.
Cauda equinaThe lower end of the spinal cord where the roots of spinal nerves have a tail-like appearance.
CecumThe pouchlike portion of the large intestine to which the ileum of the small intestine is attached.
CellThe structural and functional unit of an organism; the smallest structure capable of performing all the functions necessary for life.
Cell-mediated immunityImmunological defence provided by T cell lymphocytes that come within close proximity of their victim cells(as opposed to humoral immunity provided by the secretion of antibodies by plasma cells).
Cellular respirationThe energy-releasing metabolic pathways in a cell that oxidize organic molecules such as glucose and fatty acids.
CementumBonelike material that binds the root of a tooth to the periodontal membrane of the bony socket.
Central canalAn elongated longitudinal channel in the centre of an osteon in bone tissue that contains branches of the nutrient vessels and a nerve; also called a haversian canal.
Central nervous systemPart of the nervous system consisting of the brain and the spinal cord; CNS.
CentriolesCell organelles that form the spindle apparatus during cell division.
CentromereThe central region of a chromosome to which the chromosomal arms are attached.
CentrosomeA dense body near the nucleus of a cell that contains a pair of centrioles.
Cerebellar peduncleAn aggregation of nerve fibers connecting the cerebellum with the brain stem.
CerebellumThe portion of the brain concerned with the coordination of skeletal muscle contraction. Part of the metencephalon, it consists of two hemispheres and a central vermis.
Cerebral arterial circleAn arterial vessel that encircles the pituitary gland. It provides alternate routes for blood to reach the brain should a carotid or vertebral artery become occluded; also called the circle of Willis.
Cerebral pedunclesA paired bundle of nerve fibers along the inferior surface of the midbrain that conduct impulses between the pons and the cerebral hemispheres.
Cerebrospinal fluidA fluid produced by the choroid plexus of the ventricles of the brain. It fills the ventricles and surrounds the central nervous system in association with the meninges.
CerebrumThe largest portion of the brain, composed of the right and left hemispheres.
Ceruminous gland(sue-roo´mu1-nus) A specialised integumentary gland that secretes cerumen, or earwax, into the external auditory canal.
CervicalPertaining to the neck or a necklike portion of an organ.
Cervical ganglionA cluster of postganglionic sympathetic nerve cell bodies located in the neck, near the cervical vertebrae.
Cervical plexusA network of spinal nerves formed by the anterior branches of the first four cervical nerves.
Cervix1.The narrow necklike portion of an organ. 2.The inferior end of the uterus that adjoins the vagina(cervix of the uterus).
ChemoreceptorA neuroreceptor that is stimulated by the presence of chemical molecules.
ChemotaxisThe movement of an organism or a cell, such as a leukocyte, toward a chemical stimulus.
Cheyne-Stokes respirationBreathing characterized by rhythmic waxing and waning of the depth of respiration, with regularly occurring periods of apnea (failure to breathe).
ChiasmaA crossing of nerve tracts from one side of the CNS to the other; also called a chiasm.
ChoaneThe two posterior openings from the nasal cavity into the nasal pharynx; also called the internal nares.
CholesterolA 27-carbon steroid that serves as the precursor of steroid hormones.
CholinergicDenoting nerve endings that liberate acetylcholine as a neurotransmitter, such as those of the parasympathetic system.
ChondrocraniumThe portion of the skull that supports the brain. It is derived from endochondral bone.
ChondrocytesCartilage-forming cells.
Chordae tendineaeCordlike tendinous bands that connect papillary muscles to the leaflets of the atrioventricular valves within the ventricles of the heart.
ChoreaThe occurrence of a wide variety of rapid, complex, jerky movements that appear to be well coordinated but that are performed involuntarily.
ChorionAn extraembryonic membrane that participates in the formation of the placenta.
ChoroidThe vascular, pigmented middle layer of the wall of the eye.
Choroid plexusA mass of vascular capillaries from which cerebrospinal fluid is secreted into the ventricles of the brain.
ChromatidsDuplicated chromosomes, joined together at the centromere, that separate during cell division.
ChromatinThreadlike structures in the cell nucleus consisting primarily of DNA and protein. They represent the extended form of chromosomes during interphase.
Chromatophilic substancesClumps of rough endoplasmic reticulum in the cell bodies of neurons; also called Nissl bodies.
ChromosomesStructures in the nucleus that contain the genes for genetic expression.
ChymeThe mass of partially digested food that passes from the pylorus of the stomach into the duodenum of the small intestine.
CiliaMicroscopic hairlike processes that move in a wavelike manner on the exposed surfaces of certain epithelial cells.
Ciliary bodyA portion of the choroid layer of the eye that secretes aqueous humour. It contains the ciliary muscle.
Circadian rhythmsPhysiological changes that repeat at about 24-hour intervals. These are often synchronized with changes in the external environment, such as the day-night cycles.
Circle of WillisSee cerebral arterial circle.
CircumductionA movement of a body part that outlines a cone, such that the distal end moves in a circle while the proximal portion remains relatively stable.
CirrhosisLiver disease characterized by loss of normal microscopic structure, which is replaced by fibrosis and nodular regeneration.
ClitorisA small, erectile structure in the vulva of the female, homologous to the glans penis in the male.
Clone1.A group of cells derived from a single parent cell by mitotic cell division; since reproduction is asexual, the descendants of the parent cell are genetically identical. 2. A term used to refer to cells as separate individuals(as in white blood cells) rather than as part of a growing organ.
CNSSee central nervous system.
CoccygealPertaining to the region of the coccyx; the caudal termination of the vertebral column.
CochleaThe organ of hearing in the inner ear where nerve impulses are generated in response to sound waves.
Cochlear windowSee round window.
CodonThe sequence of three nucleotide bases in mRNA that specifies a given amino acid and determines the position of that amino acid in a polypeptide chain through complementary base pairing with an anticodon in tRNA.
CoelomThe abdominal cavity.
CoenzymeAn organic molecule, usually derived from a water-soluble vitamin, that combines with and activates specific enzyme proteins.
CofactorA substance needed for the catalytic action of an enzyme; generally used in reference to inorganic ions such as Ca++ and Mg++.
CollateralA small branch of a blood vessel or nerve fibre.
Colloid osmotic pressureOsmotic pressure exerted by plasma proteins that are present as a colloidal suspension; also called oncotic pressure.
ColonThe first portion of the large intestine.
Common bile ductA tube formed by the union of the hepatic duct and cystic duct that transports bile to the duodenum.
Compact boneTightly packed bone that is superficial to spongy bone and covered by the periosteum; also called dense bone.
ComplianceA measure of the ease with which a structure such as the lung expands under pressure; a measure of the change in volume as a function of pressure changes.
Conduction myofibersSpecialized large-diameter cardiac muscle fibers that conduct electrical impulses from the AV bundle into the ventricular walls; also called Purkinje fibers.
CondyleA rounded process at the end of a long bone that forms an articulation.
ConeA colour receptor cell in the retina of the eye.
CongenitalPresent at the time of birth.
Congestive heart failureThe inability of the heart to deliver an adequate blood flow as a result of heart disease or hypertension. This condition is associated with breathlessness, salt and water retention, and edema.
ConjunctivaThe thin membrane covering the anterior surface of the eyeball and lining the eyelids.
ConjunctivitisInflammation of the conjunctiva of the eye, which is sometimes called "pink eye."
Connective tissueOne of the four basic tissue types within the body. It is a binding and supportive tissue with abundant matrix.
Conn's syndromePrimary hyperaldosteronism; excessive secretion of aldosterone produces electrolyte imbalances.
ContralateralTaking place or originating in a corresponding part on the opposite side of the body.
Conus medullarisThe inferior, tapering portion of the spinal cord.
ConvolutionAn elevation on the surface of a structure and an infolding of the tissue upon itself.
CorneaThe transparent, convex, anterior portion of the outer layer of the eyeball.
Coronal planeA plane that divides the body into anterior and posterior portions; also called a frontal plane.
Coronary circulationThe arterial and venous blood circulation to the wall of the heart.
Coronary sinusA large venous channel on the posterior surface of the heart into which the cardiac veins drain.
Corpora quadrigeminaFour superior lobes of the midbrain concerned with visual and auditory functions.
Corpus callosumA large tract of white matter within the brain that connects the right and left cerebral hemispheres.
Corpuscle of touchA touch sensory receptor found in the papillary layer of the dermis of the skin; also called Meissner's corpuscle.
Cortex1.The outer layer of an internal organ or body structure, as of the kidney or adrenal gland. 2. The convoluted layer of grey matter that covers the surface of each cerebral hemisphere.
CorticosteroidsSteroid hormones of the adrenal cortex, consisting of glucocorticoid (such as hydrocortisone) and mineralocorticoids (such as aldosterone).
Costal cartilageThe cartilage that connects the ribs to the sternum.
CranialPertaining to the cranium.
Cranial nervesOne of 12 pairs of nerves that arise from the brain.
CraniumThe bones of the skull that enclose or support the brain and the organs of sight, hearing, and balance.
Creatine phosphateAn organic phosphate molecule in muscle cells that serves as a source of high-energy phosphate for the synthesis of ATP; also called phosphocreatine.
CrenationA notched or scalloped appearance of the red blood cell membrane caused by the osmotic loss of water from these cells.
CrestA thickened ridge of bone for the attachment of muscle.
CretinismA condition caused by insufficient thyroid secretion during prenatal development or the years of early childhood. It results in stunted growth and inadequate mental development.
Cricoid cartilageA ring-shaped cartilage that forms the inferior portion of the larynx.
CristaA crest, such as the crista galli that extends superiorly from the cribriform plate of the ethmoid bone.
CryptorchidismA developmental defect in which one or both testes fail to descend into the scrotum and, instead, remain in the body cavity.
CubitalPertaining to the antebrachium. The cubital fossa is the anterior aspect of the elbow joint.
CurareA chemical derived from plant sources that causes flaccid paralysis by blocking ACh receptor proteins in muscle cell membranes.
Cushing's syndromeSymptoms caused by the hypersecretion of adrenal steroid hormones as a result of tumours of the adrenal cortex or ACTH-secreting tumours of the anterior pituitary.
CyanosisA bluish discoloration of the skin or mucous membranes due to excessive concentration of deoxyhemoglobin; indicates inadequate oxygen concentration in the blood.
Cystic ductThe tube that transports bile from the gallbladder to the common bile duct.
CytochromeA pigment in mitochondria that transports electrons in the process of aerobic respiration.
CytokinesisThe division of the cytoplasm that occurs in mitosis and meiosis, when a parent cell divides to produce two daughter cells.
CytologyThe science dealing with the study of cells.
CytoplasmIn a cell, the protoplasm located outside of the nucleus.
CytoskeletonA latticework of structural proteins in the cytoplasm arranged in the form of microfilaments and microtubules.
DeciduousPertaining to something shed or cast off in a particular sequence. Deciduous teeth are shed and replaced by permanent teeth during development.
DecussationA crossing of nerve fibers from one side of the CNS to the other.
DeglutitionThe act of swallowing.
Delayed hypersensitivityAn allergic response in which the onset of symptoms may not occur until 2 or 3 days after exposure to an antigen. Produced by T cells, it is a type of cell-mediated immunity.
DenaturationIrreversible changes in the tertiary structure of proteins caused by heat or drastic pH changes.
DendriteA nerve cell process that transmits impulses toward a neuron cell body.
DentinThe main substance of a tooth, covered by enamel over the crown of the tooth and by cementum on the root.
DentitionThe number, arrangement, and shape of teeth.
DepolarizationThe loss of membrane polarity in which the inside of the cell membrane becomes less negative in comparison to the outside of the membrane. The term is also used to indicate the reversal of membrane polarity that occurs during the production of action potentials in nerve and muscle cells.
Dermal papillaA projection of the dermis into the epidermis.
DermisThe second, or deep, layer of skin beneath the epidermis.
Descending colonThe segment of the large intestine that descends on the left side from the level of the spleen to the level of the left iliac crest.
Diabetes insipidusA condition in which inadequate amounts of antidiuretic hormone(ADH) are secreted by the posterior pituitary. It results in the inadequate reabsorption of water by the kidney tubules and, thus, in the excretion of a large volume of dilute urine.
Diabetes mellitusThe appearance of glucose in the urine due to the presence of high plasma glucose concentrations, even in the fasting state. This disease is caused by either lack of sufficient insulin secretion or inadequate responsiveness of the target tissues to the effects of insulin.
DiapedesisThe migration of white blood cells through the endothelial walls of blood capillaries into the surrounding connective tissues.
DiaphragmA sheet like dome of muscle and connective tissue that separates the thoracic and abdominal cavities.
DiaphysisThe shaft of a long bone.
DiarthrosisA type of functionally classified joint in which the articulating bones are freely movable; also called a synovial joint.
DiastoleThe sequence of the cardiac cycle during which a heart chamber wall is relaxed.
DiencephalonA major region of the brain that includes the third ventricle, thalamus, hypothalamus, and pituitary gland.
DiffusionThe net movement of molecules or ions from regions of higher to regions of lower concentration.
DigestionThe process by which larger molecules of food substance are broken down mechanically and chemically into smaller molecules that can be absorbed.
DiploeThe spongy layer of bone positioned between the inner and outer layers of compact bone.
DiploidDenoting cells having two of each chromosome or twice the number of chromosomes that are present in sperm or ova.
DisaccharideAny of a class of double sugars; carbohydrates that yield two simple sugars, or monosaccharides, upon hydrolysis.
DistalAway from the midline or origin; the opposite of proximal.
DiureticAn agent that promotes the excretion of urine, thereby lowering blood volume and pressure.
DNADeoxyribonucleic acid; composed of nucleotide bases and deoxyribose sugar. It is found in all living cells and contains the genetic code.
DopamineA type of neurotransmitter in the central nervous system; also is the precursor of norepinephrine, another neurotransmitter molecule.
DorsalPertaining to the back or posterior portion of a body part; the opposite of ventral; also called posterior.
Dorsal root ganglionSee posterior root ganglion.
DorsiflexionMovement at the ankle as the dorsum of the foot is elevated.
Ductus arteriosusThe blood vessel that connects the pulmonary trunk and the aorta in a fetus.
Ductus deferensA tube that carries spermatozoa from the epididymis to the ejaculatory duct; also called the vas deferens or seminal duct.
Ductus venosusA fetal blood vessel that connects the umbilical vein and the inferior vena cava.
DuodenumThe first portion of the small intestine that leads from the pylorus of the stomach to the jejunum.
Dura materThe outermost meninx.
DwarfismA condition in which a person is undersized due to inadequate secretion of growth hormone.
DyspneaSubjective difficulty in breathing.
Eccrine glandA sweat gland that functions in thermoregulation.
ECGSee electrocardiogram.
EctodermThe outermost of the three primary germ layers of an embryo.
Ectopic focusAn area of the heart other than the SA node that assumes pacemaker activity.
Ectopic pregnancyEmbryonic development that occurs anywhere other than in the uterus (as in the uterine tubes or body cavity).
EffectorAn organ, such as a gland or muscle, that responds to a motor stimulation.
EfferentConveying away from the centre of an organ or structure.
Efferent arterioleAn arteriole of the renal vascular system that conducts blood away from the glomerulus of a nephron.
Efferent ductulesA series of coiled tubules through which spermatozoa are transported from the rete testis to the epididymis.
Efferent neuronSee motor neuron.
EjaculationThe discharge of semen from the male urethra that accompanies orgasm.
Ejaculatory ductA tube that transports spermatozoa from the ductus deferens to the prostatic urethra.
Elastic fibersProtein strands that are found in certain connective tissue that have contractile properties.
ElbowThe synovial joint between the brachium and the antebrachium.
ElectrocardiogramA recording of the electrical activity that accompanies the cardiac cycle; ECG or EKG.
ElectroencephalogramA recording of the brain-wave patterns or electrical impulses of the brain from electrodes placed on the scalp; EEG.
ElectrolytesIons and molecules that are able to ionize and thus carry an electric current. The most common electrolytes in the plasma are Na+, HCO3-, and K+.
ElectromyogramA recording of the electrical impulses or activity of skeletal muscles using surface electrodes; EMG.
ElectrophoresisA biochemical technique in which different molecules can be separated and identified by their rate of movement in an electric field.
ElephantiasisA disease caused by infection with a nematode worm in which the larvae block lymphatic drainage and produce edema; the lower areas of the body can become enormously swollen as a result.
EmbryologyThe study of prenatal development from conception through the eighth week in utero.
EMGSee electromyogram.
EmphysemaA lung disease in which the alveoli are destroyed and the remaining alveoli become larger. It results in decreased vital capacity and increased airway resistance.
EmulsificationThe process of producing an emulsion or fine suspension; in the small intestine, fat globules are emulsified by the detergent action of bile.
EnamelThe outer dense substance covering the crown of a tooth.
EndergonicDenoting a chemical reaction that requires the input of energy from an external source in order to proceed.
EndocardiumThe endothelial lining of the heart chambers and valves.
Endochondral boneDenoting bones that develop as hyaline cartilage models first and that are then ossified.
Endocrine glandA ductless, hormone-producing gland that is part of the endocrine system.
EndocytosisA general term for the cellular uptake of particles that are too large to cross the cell membrane. See also phagocytosis and pinocytosis.
EndodermThe innermost of the three primary germ layers of an embryo.
EndogenousDenoting a product or process arising from within the body (as opposed to exogenous products or influences from external sources).
EndolymphA fluid within the membranous labyrinth and cochlear duct of the inner ear that aids in the conduction of vibrations involved in hearing and the maintenance of equilibrium.
EndometriumThe inner lining of the uterus.
EndomysiumThe connective tissue sheath that surrounds each skeletal muscle fibre, separating the muscle cells from one another.
EndoneuriumThe connective tissue sheath that surrounds each nerve fibers, separating the nerve fibers one from another within a nerve.
Endoplasmic reticulumA cytoplasmic organelle composed of a network of canals running through the cytoplasm of a cell.
EndorphinsA group of endogenous opiate molecules that may act as a natural analgesic.
EndotheliumThe layer of epithelial tissue that forms the thin inner lining of blood vessels and heart chambers.
EndotoxinA toxin found within certain types of bacteria that is able to stimulate the release of endogenous pyrogen and produce a fever.
EnkephalinsShort polypeptides, containing five amino acids, that have analgesic effects and that may function as neurotransmitters in the brain. The two known enkephalins (which differ in only one amino acid) are endorphins.
EntericThe term referring to the small intestine.
EntropyThe energy of a system that is not available to perform work. A measure of the degree of disorder in a system, entropy increases whenever energy is transformed.
EnzymeA protein catalyst that increases the rate of specific chemical reactions.
EosinophilA type of white blood cell characterized by the presence of cytoplasmic granules that become stained by acidic eosin dye. Eosinophils normally constitute about 2% to 4% of the white blood cells.
EpicardiumA thin, outer layer of the heart; also called the visceral pericardium.
EpicondyleA projection of bone above a condyle.
EpidermisThe outermost layer of the skin, composed of several stratified squamous epithelial layers.
EpididymisA highly coiled tube located along the posterior border of the testis. It stores spermatozoa and transports them from the seminiferous tubules of the testis to the ductus deferens.
Epidural spaceA space between the spinal dura mater and the bone of the vertebral canal.
EpiglottisA leaf like structure positioned on top of the larynx. It covers the glottis during swallowing.
EpimysiumA fibrous outer sheath of connective tissue surrounding a skeletal muscle.
EpinephrineA hormone secreted from the adrenal medulla resulting in actions similar to those resulting from sympathetic nervous system stimulation; also called adrenaline.
EpineuriumA fibrous outer sheath of connective tissue surrounding a nerve.
Epiphyseal plateA hyaline cartilaginous layer located between the epiphysis and diaphysis of a long bone. It functions as a longitudinal growing region.
EpiphysisThe end segment of a long bone, separated from the diaphysis early in life by an epiphyseal plate but later becoming part of the larger bone.
EpisiotomyAn incision of the perineum at the end of the second stage of labour to facilitate delivery and to avoid tearing the perineum.
Epithelial tissueOne of the four basic tissue types; the type of tissue that covers or lines all exposed body surfaces.
EponychiumThe thin layer of stratum corneum of the epidermis of the skin that overlaps and protects the lunula of the nail.
EPSPExcitatory postsynaptic potential; a graded depolarization of a postsynaptic membrane in response to stimulation by a neurotransmitter chemical. EPSPs can be summated but can be transmitted only over short distances. They can stimulate the production of action potentials when a threshold level of depolarization has been attained.
Erythroblastosis fetalisHemolytic anemia in an Rh positive newborn caused by maternal antibodies against the Rh factor that have crossed the placenta.
ErythrocyteA red blood cell.
EsophagusA tubular portion of the GI tract that leads from the pharynx to the stomach as it passes through the thoracic cavity.
Essential amino acidsThose eight amino acids in adults or nine amino acids in children that cannot be made by the human body; therefore, they must be obtained in the diet.
EstrogensAny of several female sex hormones secreted from the ovarian (graafian) follicle.
Estrus cycleCyclic changes in the structure and function of the ovaries and female reproductive tract of mammals other than humans, accompanied by periods of "heat" (estrus) or sexual receptivity. Estrus is the equivalent of the human menstrual cycle but differs from the human menstrual cycle in that the endometrium is not shed with accompanying bleeding.
EtiologyThe study of cause, especially of disease, including the origin and what pathogens, if any, are involved.
EversionA movement of the foot in which the sole is turned outward.
ExergonicDenoting chemical reactions that liberate energy.
Exocrine glandA gland that secretes its product to an epithelial surface, directly or through ducts.
ExocytosisThe process of cellular secretion in which the secretory products are contained within a membrane-enclosed vesicle. The vesicle fuses with the cell membrane so that the lumen of the vesicle is open to the extracellular environment.
ExpirationThe process of expelling air from the lungs through breathing out; also called exhalation.
ExtensionA movement that increases the angle between parts of a joint.
ExtensorA muscle that, upon contraction, increases the angle of a joint.
External acoustic meatusAn opening through the temporal bone that connects with the tympanum and the middle-ear chamber and through which sound vibrations pass; also called the external auditory meatus.
ExteroceptorsSensory receptors that are sensitive to changes in the external environment (as opposed to interoceptors).
Extraocular musclesThe muscles that insert into the sclera of the eye and that act to change the position of the eye in its orbit (as opposed to the intraocular muscles, such as those of the iris and ciliary body within the eye).
ExtrinsicPertaining to an outside or external origin.
Face1. The anterior aspect of the head not supporting or covering the brain. 2. The exposed surface of a structure.
FacetA small, smooth surface of a bone where articulation occurs.
Facilitated diffusionThe carrier-mediated transport of molecules through the cell membrane along the direction of their concentration gradients. It does not require the expenditure of metabolic energy.
FADFlavin adenine dinucleotide; a coenzyme derived from riboflavin that participates in electron transport within the mitochondria.
Falciform ligamentAn extension of parietal peritoneum that separates the right and left lobes of the liver.
Fallopian tubeSee uterine tube.
False vocal cordsThe supporting folds of tissue for the true vocal cords within the larynx.
Falx cerebelliA fold of the dura mater anchored to the occipital bone. It projects inward between the cerebellar hemispheres.
Falx cerebriA fold of dura mater anchored to the crista galli of the ethmoid bone. It extends between the right and left cerebral hemispheres.
FasciaA tough sheet of fibrous tissue binding the skin to underlying muscles or supporting and separating muscles.
FasciculusA small bundle of muscle or nerve fibers.
FaucesThe passageway between the mouth and the pharynx.
FecesMaterial expelled from the GI tract during defecation, composed of undigested food residue, bacteria, and secretions; also called stool.
FertilizationThe fusion of an ovum and spermatozoon.
FetusA prenatal human after 8 weeks of development.
FibrillationA condition of cardiac muscle characterized electrically by random and continuously changing patterns of electrical activity and resulting in the inability of the myocardium to contract as a unit and pump blood. It can be fatal if it occurs in the ventricles.
FibrinThe insoluble protein formed from fibrinogen by the enzymatic action of thrombin during the process of blood clot formation.
FibrinogenA soluble plasma protein that serves as the precursor of fibrin; also called factor I.
FibroblastAn elongated connective tissue cell with cytoplasmic extensions that is capable of forming collagenous fibers or elastic fibers.
Fibrous jointA type of articulation bound by fibrous connective tissue that allows little or no movement (e.g., a syndesmosis).
Filiform papillaeNumerous small projections over the entire surface of the tongue in which taste buds are absent.
Filum terminaleA fibrous, threadlike continuation of the pia mater, extending inferiorly from the terminal end of the spinal cord to the coccyx.
FimbriaeFringelike extensions from the borders of the open end of the uterine tube.
FissureA groove or narrow cleft that separates two parts, such as the cerebral hemispheres of the brain.
FlagellumA whip like structure that provides motility for sperm.
Flare-and-wheal reactionA cutaneous reaction to skin injury or the administration of antigens, produced by release of histamine and related molecules and characterized by local edema and a red flare.
FlavoproteinA conjugated protein containing a flavin pigment that is involved in electron transport within the mitochondria.
FlexionA movement that decreases the angle between parts of a joint.
FlexorA muscle that decreases the angle of a joint when it contracts.
FontanelA membranous-covered region on the skull of a fetus or baby where ossification has not yet occurred; commonly called a soft spot.
FootThe terminal portion of the lower extremity, consisting of the tarsal bones, metatarsal bones, and phalanges.
ForamenAn opening in an anatomical structure, usually in a bone, for the passage of a blood vessel or a nerve.
Foramen ovaleAn opening through the interatrial septum of the fetal heart.
ForearmThe portion of the upper extremity between the elbow and the wrist; also called the antebrachium.
Fornix1. A recess around the cervix of the uterus where it protrudes into the vagina. 2. A tract within the brain connecting the hippocampus with the mamillary bodies.
FossaA depressed area, usually on a bone.
Fourth ventricleA cavity within the brain, between the cerebellum and the medulla oblongata and the pons, containing cerebrospinal fluid.
Fovea centralisA depression on the macula lutea of the eye, where only cones are located; the area of keenest vision.
FrenulumA membranous structure that serves to anchor and limit the movement of a body part.
Frontal1. Pertaining to the region of the forehead. 2. A plane through the body, dividing the body into anterior and posterior portions; also called the coronal plane.
FSHFollicle-stimulating hormone; one of the two gonadotropic hormones secreted from the anterior pituitary. In females, FSH stimulates the development of the ovarian follicles; in males, it stimulates the production of sperm in the seminiferous tubules.
Fungiform papillaeFlattened, mushroom-shaped projections interspersed over the surface of the tongue in which taste buds are present.
GABAGamma-aminobutyric acid; believed to function as an inhibitory neurotransmitter in the central nervous system.
GallbladderA pouch like organ attached to the underside of the liver in which bile secreted by the liver is stored and concentrated.
GameteA haploid sex cell; either an egg cell or a sperm cell.
GanglionAn aggregation of nerve cell bodies occurring outside the central nervous system.
Gastric intrinsic factorA glycoprotein secreted by the stomach that is needed for the absorption of vitamin B12.
GastrinA hormone secreted by the stomach that stimulates the gastric secretion of hydrochloric acid and pepsin.
Gastrointestinal tractThe portion of the digestive tract that includes the stomach and the small and large intestines.
GatesStructures composed of one or more protein molecules that regulate the passage of ions through channels within the cell membrane. Gates may be chemically regulated (by neurotransmitters) or voltage regulated (in which case they open in response to a threshold level of depolarization).
Genetic recombinationThe formation of new combinations of genes, as by crossing-over between homologous chromosomes.
Genetic transcriptionThe process by which RNA is produced with a sequence of nucleotide bases that is complementary to a region of DNA.
Genetic translationThe process by which proteins are produced with amino acid sequences specified by the sequence of codons in messenger RNA.
GigantismAbnormal body growth as a result of the excessive secretion of growth hormone.
GingivaThe fleshy covering over the mandible and maxilla through which the teeth protrude within the mouth; also called the gum.
GlandAn organ that produces a specific substance or secretion.
Glans penisThe enlarged, sensitive, distal end of the penis.
Gliding jointA type of synovial joint in which the articular surfaces are flat, permitting only side-to-side and back-and-forth movements.
Glomerular capsuleThe double-walled proximal portion of a renal tubule that encloses the glomerulus of a nephron; also called Bowman's capsule.
Glomerular filtration rateThe volume of filtrate produced per minute by both kidneys.
Glomerular ultrafiltrateFluid filtered through the glomerular capillaries into the glomerular capsule of the kidney tubules.
GlomerulonephritisInflammation of the renal glomeruli, associated with fluid retention, edema, hypertension, and the appearance of protein in the urine.
GlomerulusA coiled tuft of capillaries surrounded by the glomerular capsule that filtrates urine from the blood.
GlottisA slit like opening into the larynx, positioned between the true vocal cords.
GlucagonA polypeptide hormone secreted by the alpha cells of the pancreatic islets. It acts primarily on the liver to promote glycogenolysis and raise blood glucose levels.
GlucocorticoidsSteroid hormones secreted by the adrenal cortex (corticosteroids). They affect the metabolism of glucose, protein, and fat and also have anti-inflammatory and immunosuppressive effects. The major glucocorticoid in humans is hydrocortisone (cortisol).
GluconeogenesisThe formation of glucose from noncarbohydrate molecules, such as amino acids and lactic acid.
GlycerolA 3-carbon alcohol that serves as a building block of fats.
GlycogenA polysaccharide of glucose-also called animal starch-produced primarily in the liver and skeletal muscles. Similar to plant starch in composition, glycogen contains more highly branched chains of glucose subunits than does plant starch.
GlycogenesisThe formation of glycogen from glucose.
GlycogenolysisThe hydrolysis of glycogen to glucose 1-phosphate, which can be converted to glucose 6-phosphate, which then may be oxidized via glycolysis or (in the liver) converted to free glucose.
GlycolysisThe metabolic pathway that converts glucose to pyruvic acid; the final products are two molecules of pyruvic acid and two molecules of reduced NAD, with a net gain of two ATP molecules. In anaerobic respiration, the reduced NAD is oxidized by the conversion of pyruvic acid to lactic acid. In aerobic respiration, pyruvic acid enters the Krebs cycle in mitochondria and reduced NAD is ultimately oxidized to yield water.
GlycosuriaThe excretion of an abnormal amount of glucose in the urine (urine normally only contains trace amounts of glucose).
Goblet cellA unicellular mucus-secreting gland that is associated with columnar epithelia; also called a mucous cell.
Golgi apparatusA network of stacked, flattened membranous sacs within the cytoplasm of cells. Its major function is to concentrate and package proteins for secretion from the cell.
Golgi tendon organA sensory receptor found near the junction of tendons and muscles.
GonadA reproductive organ, testis or ovary, that produces gametes and sex hormones.
Gonadotropic hormonesHormones of the anterior pituitary that stimulate gonadal function-the formation of gametes and secretion of sex steroids. The two gonadotropins are FSH (follicle-stimulating hormone) and LH (luteinizing hormone), which are essentially the same in males and females.
Graafian follicleA mature ovarian follicle, containing a single fluid-filled cavity, with the ovum located toward one side of the follicle and perched on top of a hill of granulosa cells.
Granular leukocytesLeukocytes with granules in the cytoplasm; on the basis of the staining properties of the granules, these cells are classified as neutrophils, eosinophils, or basophils.
Graves' diseaseA hyperthyroid condition believed to be caused by excessive stimulation of the thyroid gland by autoantibodies; it is associated with exophthalmos (bulging eyes), high pulse rate, high metabolic rate, and other symptoms of hyperthyroidism.
Grey matterThe region of the central nervous system composed of nonmyelinated nerve tissue.
Greater omentumA double-layered peritoneal membrane that originates on the greater curvature of the stomach. It hangs inferiorly like an apron over the contents of the abdominal cavity.
Gross anatomyThe branch of anatomy concerned with structures of the body that can be studied without a microscope.
Growth hormoneA hormone secreted by the anterior pituitary that stimulates growth of the skeleton and soft tissues during the growing years and that influences the metabolism of protein, carbohydrate, and fat throughout life.
GustatoryPertaining to the sense of taste.
GutThe GI tract or a portion thereof; generally used in reference to the embryonic digestive tube, consisting of the foregut, midgut, and hindgut.
GyrusA convoluted elevation or ridge.
HairA threadlike appendage of the epidermis consisting of keratinized dead cells that have been pushed up from a dividing basal layer.
Hair cellsSpecialised receptor nerve endings for detecting sensations, such as in the spiral organ (organ of Corti).
Hair follicleA tubular depression in the dermis of the skin in which a hair develops.
HandThe terminal portion of the upper extremity, containing the carpal bones, metacarpal bones, and phalanges.
HaploidA cell that has one of each chromosome type and therefore half the number of chromosomes present in most other body cells; only the gametes (sperm and ova) are haploid.
HaptensSmall molecules that are not antigenic by themselves, but which-when combined with proteins-become antigenic and thus capable of stimulating the production of specific antibodies.
Hard palateThe bony partition between the oral and nasal cavities, formed by the maxillae and palatine bones and lined by mucous membrane.
HaustraSacculations or pouches of the colon.
Haversian canalSee central canal.
Haversian systemSee osteon.
Hay feverA seasonal type of allergic rhinitis caused by pollen; it is characterized by itching and tearing of the eyes, swelling of the nasal mucosa, attacks of sneezing, and often by asthma.
HeadThe uppermost portion of a human that contains the brain and major sense organs.
HeartA four-chambered, muscular pumping organ positioned in the thoracic cavity, slightly to the left of midline.
Heart murmurAn auscultatory sound of cardiac or vascular origin, usually caused by an abnormal flow of blood in the heart as a result of structural defects of the valves or septum.
Helper T cellsA subpopulation of T cells (lymphocytes) that helps to stimulate the antibody production of B lymphocytes by antigens.
HematocritThe ratio of packed red blood cells to total blood volume in a centrifuged sample of blood, expressed as a percentage.
HemeThe iron-containing red pigment that, together with the protein globin, forms hemoglobin.
HemoglobinThe pigment of red blood cells constituting about 33% of the cell volume that transports oxygen and carbon dioxide.
HemopoiesisThe production of red blood cells.
HeparinA mucopolysaccharide found in many tissues, but most abundantly in the lungs and liver, that is used medically as an anticoagulant.
Hepatic ductA duct formed from the fusion of several bile ducts that drain bile from the liver. The hepatic duct merges with the cystic duct from the gallbladder to form the common bile duct.
Hepatic portal circulationThe return of venous blood from the digestive organs and spleen through a capillary network within the liver before draining into the heart.
HepatitisInflammation of the liver.
Hepatopancreatic ampullaA small, elevated area within the duodenum where the combined pancreatic and common bile duct empties; also called the ampulla of Vater.
Hering-Breuer reflexA reflex in which distension of the lungs stimulates stretch receptors, which in turn act to inhibit further distension of the lungs.
HermaphroditeAn organism having both testes and ovaries.
HeterochromatinA condensed, inactive form of chromatin.
Hiatal herniaA protrusion of an abdominal structure through the esophageal hiatus of the diaphragm into the thoracic cavity.
HiatusAn opening or fissure; a foramen.
High-density lipoproteins (HDLs)Combinations of lipids and proteins that migrate rapidly to the bottom of a test tube during centrifugation. HDLs are carrier proteins for lipids, such as cholesterol, that appear to offer some protection from atherosclerosis.
HilumA concave or depressed area where vessels or nerves enter or exit an organ; also called hilus.
Hinge jointA type of synovial articulation characterized by a convex surface of one bone fitting into a concave surface of another such that movement is confined to one plane, as in the knee or interphalangeal joint.
HistamineA compound secreted by tissue mast cells and other connective tissue cells that stimulates vasodilation and increases capillary permeability. It is responsible for many of the symptoms of inflammation and allergy.
HistologyMicroscopic anatomy of the structure and function of tissues.
HomeostasisThe dynamic constancy of the internal environment, the maintenance of which is the principal function of physiological regulatory mechanisms. The concept of homeostasis provides a framework for understanding most physiological processes.
Homologous chromosomesThe matching pairs of chromosomes in a diploid cell.
HormoneA chemical substance produced in an endocrine gland and secreted into the bloodstream to cause an effect in a specific target organ.
Humoral immunityThe form of acquired immunity in which antibody molecules are secreted in response to antigenic stimulation (as opposed to cell mediated immunity); also called antibody-mediated immunity.
Hyaline cartilageA cartilage with a homogeneous matrix. It is the most common type, occurring at the articular ends of bones, in the trachea, and within the nose. Most of the bones in the body are formed from hyaline cartilage.
Hyaline membrane diseaseA disease affecting premature infants who lack pulmonary surfactant, it is characterized by collapse of the alveoli (atelectasis) and pulmonary edema; also called respiratory distress syndrome.
HydrocortisoneThe principal corticosteroid hormone secreted by the adrenal cortex, with glucocorticoid action; also called cortisol.
HydrophilicDenoting a substance that readily absorbs water; literally, "water loving."
HydrophobicDenoting a substance that repels, and that is repelled by, water; "water fearing."
HymenA developmental remnant (vestige) of membranous tissue that partially covers the vaginal opening.
Hyperbaric oxygenOxygen gas present at greater than atmospheric pressure.
HypercapniaExcessive concentration of carbon dioxide in the blood.
HyperextensionExtension beyond the normal anatomical position or 180∞.
HyperglycemiaAn abnormally increased concentration of glucose in the blood.
HyperkalemiaAn abnormally high concentration of potassium in the blood.
HyperopiaA refractive disorder in which rays of light are brought to a focus behind the retina as a result of the eyeball being too short; also called farsightedness.
HyperplasiaAn increase in organ size due to an increase in cell numbers as a result of mitotic cell division (in contrast to hypertrophy).
HyperpolarizationAn increase in the negativity of the inside of a cell membrane with respect to the resting membrane potential.
HypersensitivityAnother name for allergy; abnormal immune response that may be immediate (due to antibodies of the IgE class) or delayed (due to cell-mediated immunity).
HypertensionElevated or excessive blood pressure.
HypertonicDenoting a solution with a greater solute concentration and thus a greater osmotic pressure than plasma.
HypertrophyGrowth of an organ due to an increase in the size of its cells (in contrast to hyperplasia).
HyperventilationA high rate and depth of breathing that results in a decrease in the blood carbon dioxide concentration to below normal.
HypodermisA layer of fat beneath the dermis of the skin.
HyponychiumA thickened, supportive layer of stratum corneum at the distal end of a digit under the free edge of the nail.
Hypothalamic hormonesHormones produced by the hypothalamus. These include antidiuretic hormone and oxytocin, which are secreted by the posterior pituitary, and both releasing and inhibiting hormones that regulate the secretions of the anterior pituitary.
Hypothalamo-hypophyseal portal systemA vascular system that transports releasing and inhibiting hormones from the hypothalamus to the anterior pituitary.
Hypothalamo-hypophyseal tractThe tract of nerve fibers (axons) that transports antidiuretic hormone and oxytocin from the hypothalamus to the posterior pituitary.
HypothalamusA portion of the forebrain within the diencephalon that lies below the thalamus, where it functions as an autonomic nerve centre and regulates the pituitary gland.
Hypovolemic shockA rapid fall in blood pressure as a result of diminished blood volume.
HypoxemiaA low oxygen concentration of the arterial blood.
Ileocecal valveA modification of the mucosa at the junction of the small and large intestine that forms a one-way passage and prevents the backflow of food materials.
IleumThe terminal portion of the small intestine between the jejunum and cecum.
Immediate hypersensitivityHypersensitivity (allergy) mediated by antibodies of the IgE class that results in the release of histamine and related compounds from tissue cells.
ImmunizationThe process of increasing one's resistance to pathogens. In active immunity a person is injected with antigens that stimulate the development of clones of specific B or T lymphocytes; in passive immunity a person is injected with antibodies produced by another organism.
ImmunoassayAny of a number of laboratory or clinical techniques that employ the specific binding between an antigen and its homologous antibody in order to identify and quantify a substance in a sample.
ImmunoglobulinsSubclasses of the gamma globulin fraction of plasma proteins that have antibody functions, providing humoral immunity.
ImmunosurveillanceThe concept that the immune system recognizes and attacks malignant cells that produce antigens not recognized as "self." This function is believed to be cell mediated rather than humoral.
ImplantationThe process by which a blastocyst attaches itself to and penetrates into the endometrium of the uterus.
IncusThe middle of three auditory ossicles within the middle-ear chamber; commonly called the anvil.
Inferior vena cavaA large systemic vein that collects blood from the body regions inferior to the level of the heart and returns it to the right atrium.
InfundibulumThe stalk that attaches the pituitary gland to the hypothalamus of the brain.
IngestionThe process of taking food or liquid into the body by way of the oral cavity.
InguinalPertaining to the groin region.
Inguinal canalThe circular passageway in the abdominal wall through which a testis descends into the scrotum.
InhibinA polypeptide hormone secreted by the testes that is believed to specifically exert negative feedback inhibition of FSH secretion from the anterior pituitary.
InositolA sugar like B-complex vitamin. Inositol triphosphate is believed to act as a second messenger in the action of some hormones.
InsertionThe more movable attachment of a muscle, usually more distal.
InspirationThe act of breathing air into the alveoli of the lungs; also called inhalation.
InsulaA deep, paired cerebral lobe.
InsulinA polypeptide hormone secreted by the beta cells of the pancreatic islets that promotes the anabolism of carbohydrates, fat, and protein. Insulin acts to promote the cellular uptake of blood glucose and, therefore, to lower the blood glucose concentration; insulin deficiency results in hyperglycemia and diabetes mellitus.
IntegumentThe skin; the largest organ of the body.
Intercalated discA thickened portion of the sarcolemma that extends across a cardiac muscle fibre, indicating the boundary between cells.
Intercellular substanceThe matrix or material between cells that largely determines tissue types.
InterferonsA group of small proteins that inhibit the multiplication of viruses inside host cells and that also have antitumor properties.
Internal earThe innermost portion or chamber of the ear, containing the cochlea and the vestibular organs.
InterneuronsMultipolar neurons interposed between sensory (afferent) and motor (efferent) neurons and confined entirely within the central nervous system; also called association neurons.
InteroceptorsSensory receptors that respond to changes in the internal environment (as opposed to exteroceptors).
InterphaseThe interval between successive cell divisions, during which time the chromosomes are in an extended state and are active in directing RNA synthesis.
Interstitial cellsCells located in the interstitial tissue between adjacent convolutions of the seminiferous tubules of the testes; they secrete androgens (mainly testosterone); also called cells of Leydig.
Intervertebral discA pad of fibrocartilage located between the bodies of adjacent vertebrae.
Intestinal cryptA simple tubular digestive gland opening onto the surface of the intestinal mucosa that secretes digestive enzymes; also called the crypt of Lieberkühn.
Intrafusal fibersModified muscle fibers that are encapsulated to form muscle spindle organs, which are muscle stretch receptors.
Intramembranous ossificationSee membranous bone.
Intrapleural spaceAn actual or potential space between the visceral pleural membrane covering the lungs and the somatic pleural membrane lining the thoracic wall.
IntrinsicSituated within or pertaining to internal origin.
InulinA polysaccharide of fructose, produced by certain plants, that is filtered by the human kidneys but neither reabsorbed nor secreted. The clearance rate of injected insulin is thus used to measure the glomerular filtration rate.
InversionA movement of the foot in which the sole is turned inward.
In vitroOccurring outside the body, in a test tube or other artificial environment.
In vivoOccurring within the body.
IonAn atom or group of atoms that has either lost or gained electrons and thus has a net positive or a net negative charge.
IonizationThe dissociation of a solute to form ions.
IpsilateralOn the same side (as opposed to contralateral).
IPSPInhibitory postsynaptic potential; hyperpolarization of the postsynaptic membrane in response to a particular neurotransmitter chemical, which makes it more difficult for the postsynaptic cell to attain a threshold level of depolarization required to produce action potentials. It is responsible for postsynaptic inhibition.
IrisThe pigmented portion of the vascular tunic of the eye that surrounds the pupil and regulates its diameter.
IschemiaA rate of blood flow to an organ that is inadequate to supply sufficient oxygen and maintain aerobic respiration in that organ.
Islets of LangerhansSee pancreatic islets.
IsoenzymesEnzymes, usually produced by different organs, that catalyze the same reaction but that differ from each other in amino acid composition.
Isometric contractionMuscle contraction in which there is no appreciable shortening of the muscle.
Isotonic contractionMuscle contraction in which the muscle shortens in length and maintains approximately the same amount of tension throughout the shortening process.
Isotonic solutionA solution having the same total solute concentration, osmolality, and osmotic pressure as the solution with which it is compared; a solution with the same solute concentration and osmotic pressure as plasma.
IsthmusA narrow neck or portion of tissue connecting two structures.
JaundiceA condition characterized by high blood bilirubin levels and staining of the tissues with bilirubin, which imparts a yellow colour to the skin and mucous membranes.
JejunumThe middle portion of the small intestine, located between the duodenum and the ileum.
Joint capsuleThe fibrous tissue that encloses the joint cavity of a synovial joint.
KeratinAn insoluble protein present in the epidermis and in epidermal derivatives, such as hair and nails.
KetoacidosisA type of metabolic acidosis resulting from the excessive production of ketone bodies, as in diabetes mellitus.
KetogenesisThe production of ketone bodies.
Ketone bodiesThe substances derived from fatty acids via acetyl coenzyme A in the liver; namely, acetone, acetoacetic acid, and b-hydroxybutyric acid. Ketone bodies are oxidized by skeletal muscles for energy.
KetosisAn abnormal elevation in the blood concentration of ketone bodies that does not necessarily produce acidosis.
KidneyOne of a pair of organs of the urinary system that contains nephrons and that filters wastes from the blood in the formation of urine.
KilocalorieA unit of measurement equal to 1000 calories, which are units of heat (a kilocalorie is the amount of heat required to raise the temperature of 1 kilogram of water by 1 C∞). In nutrition, the kilocalorie is called a big calorie (Calorie).
KinesiologyThe study of body movement.
Klinefelter's syndromeAn abnormal condition of male sex characteristics due to the presence of an extra X chromosome (genotype XXY).
KneeA region in the lower extremity between the thigh and the leg that contains a synovial hinge joint.
Krebs cycleA cyclic metabolic pathway in the matrix of mitochondria by which the acetic acid part of acetyl CoA is oxidized and substrates provided for reactions that are coupled to the formation of ATP.
Kupffer cellsPhagocytic cells lining the sinusoids of the liver that are part of the body immunity system.
Labial frenulumA longitudinal fold of mucous membrane that attaches the lips to the gum along the midline of both the upper and lower lip.
Labia majoraA portion of the external genitalia of a female consisting of two longitudinal folds of skin extending downward and backward from the mons pubis.
Labia minoraTwo small folds of skin, devoid of hair and sweat glands, lying between the labia major of the external genitalia of a female.
LabyrinthAn intricate structure consisting of interconnecting passages (e.g., the bony and membranous labyrinths of the inner ear.
Lacrimal canaliculusA drainage duct for tears, located at the medial corner of an eyelid. It conveys the tears medially into the nasolacrimal sac.
Lacrimal glandA tear-secreting gland, located on the superior lateral portion of the eyeball underneath the upper eyelid.
LactationThe production and secretion of milk by the mammary glands.
LactealA small lymphatic duct associated with a villus of the small intestine.
LactoseMilk sugar; a disaccharide of glucose and galactose.
Lactose intoleranceA disorder resulting in the inability to digest lactose because of an enzyme, lactase, deficiency. Symptoms include bloating, intestinal gas, nausea, diarrhea, and cramps.
LacunaA small, hollow chamber that houses an osteocyte in mature bone tissue or a chondrocyte in cartilage tissue.
Lambdoidal sutureThe immovable joint in the skull between the parietal bones and the occipital bone.
LamellaA concentric ring of matrix surrounding the central canal in an osteon of mature bone tissue.
Lamellated corpuscleA sensory receptor for pressure, found in tendons, around joints, and in visceral organs; also called a pacinian corpuscle.
LaminaA thin plate of bone that extends superiorly from the body of a vertebra to form either side of the arch of a vertebra.
LanugoShort, silky fetal hair, which may be present for a short time on a premature infant.
Large intestineThe last major portion of the GI tract, consisting of the cecum, colon, rectum, and anal canal.
LaryngopharynxThe inferior or lower portion of the pharynx in contact with the larynx. 686
LarynxThe structure located between the pharynx and trachea that houses the vocal cords; commonly called the voice box.
LateralPertaining to the side; farther from the mid plane.
Lateral ventricleA cavity within the cerebral hemisphere of the brain that is filled with cerebrospinal fluid.
L-dopaLevodopa; a derivative of the amino acid tyrosine. It serves as the precursor for the neurotransmitter molecule dopamine and is given to patients with Parkinson's disease to stimulate dopamine production.
LegThe portion of the lower extremity between the knee and ankle.
LensA transparent refractive organ of the eye positioned posterior to the pupil and iris.
LesionA wounded or damaged area.
Lesser omentumA peritoneal fold of tissue extending from the lesser curvature of the stomach to the liver.
LeukocyteA white blood cell; variant spelling, leucocyte.
LigamentA tough cord or fibrous band of connective tissue that binds bone to bone to strengthen and provide flexibility to a joint. It also may support viscera.
Limbic systemA portion of the brain concerned with emotions and autonomic activity.
Linea albaA vertical fibrous band extending down the anterior medial portion of the abdominal wall.
Lingual frenulumA longitudinal fold of mucous membrane that attaches the tongue to the floor of the oral cavity.
LipogenesisThe formation of fat or triglycerides.
LipolysisThe hydrolysis of triglycerides into free fatty acids and glycerol.
LiverA large visceral organ inferior to the diaphragm in the right hypochondriac region. The liver detoxifies the blood and modifies the blood plasma concentration of glucose, triglycerides, ketone bodies, and proteins.
Low-density lipoproteinsPlasma proteins that transport triglycerides and cholesterol. They are believed to contribute to arteriosclerosis.
Lower extremityA lower appendage, including the hip, thigh, knee, leg, and foot.
LumbarPertaining to the region of the loins.
Lumbar plexusA network of nerves formed by the anterior branches of spinal nerves L1 through L4.
LumenThe space within a tubular structure through which a substance passes.
LungOne of the two major organs of respiration positioned within the thoracic cavity on either side of the mediastinum.
Lung surfactantA mixture of lipoproteins (containing phospholipids) secreted by type II alveolar cells into the alveoli of the lungs. It lowers surface tension and prevents collapse of the lungs as occurs in hyaline membrane disease, in which surfactant is absent.
LunulaThe half-moon-shaped whitish area at the proximal portion of a nail.
Luteinizing hormone(LH) A hormone secreted by the adenohypophysis (anterior lobe) of the pituitary gland that stimulates ovulation and the secretion of progesterone by the corpus luteum. It also influences mammary gland milk secretion in females and stimulates testosterone secretion by the testes in males.
Lymph (limf)A clear, plasma like fluid that flows through lymphatic vessels.
Lymphatic systemThe lymphatic vessels and lymph nodes.
Lymph nodeA small, ovoid mass of reticular tissue located along the course of lymph vessels.
LymphocyteA type of white blood cell characterized by agranular cytoplasm. Lymphocytes usually constitute about 20% to 25% of the white blood cell count.
LymphokinesA group of chemicals released from T cells that contribute to cell-mediated immunity.
LysosomesOrganelles containing digestive enzymes and responsible for intracellular digestion.
MacromoleculesLarge molecules; a term that usually refers to protein, RNA, and DNA.
MacrophageA wandering phagocytic cell.
Macula luteaA yellowish depression in the retina of the eye that contains the fovea centralis, the area of keenest vision.
MalignantThreatening to life; virulent. Of a tumor, cancerous, tending to metastasize.
MalleusThe first of three auditory ossicles that attaches to the tympanum; commonly called the hammer.
Mammary glandThe gland of the female breast responsible for lactation and nourishment of the young.
MarrowThe soft connective tissue found within the inner cavity of certain bones that produces red blood cells.
Mast cellA type of connective tissue cell that produces and secretes histamine and heparin and promotes local inflammation.
MasticationThe chewing of food.
MatrixThe intercellular substance of a tissue.
Maximal oxygen uptakeThe maximum amount of oxygen that can be consumed by the body per unit time during heavy exercise.
MeatusA passageway or opening into a structure.
MechanoreceptorA sensory receptor that responds to a mechanical stimulus.
MedialToward or closer to the mid plane of the body.
MediastinumThe partition in the centre of the thorax between the two pleural cavities.
MedullaThe centre portion of an organ.
Medulla oblongataA portion of the brain stem located between the spinal cord and the pons.
MedullaryThe hollow core of the diaphysis of a long bone in which marrow is found.
MegakaryocyteA bone marrow cell that gives rise to blood platelets.
MeiosisA specialized type of cell division by which gametes or haploid sex cells are formed.
Meissner's corpuscleSee corpuscle of touch.
MelaninA dark pigment found within the epidermis or epidermal derivatives of the skin.
MelanocyteA specialized melanin-producing cell found in the deepest layer of the epidermis.
MelanomaA dark, malignant tumor of the skin that frequently forms in moles.
MelatoninA hormone secreted by the pineal gland that produces lightening of the skin in lower vertebrates and that may contribute to the regulation of gonadal function in mammals. Secretion follows a circadian rhythm and peaks at night.
Membrane potentialThe potential difference or voltage that exists between the inner and outer sides of a cell membrane. It exists in all cells but is capable of being changed by excitable cells (neurons and muscle cells).
Membranous boneBone that forms from membranous connective tissue rather than from cartilage.
Membranous labyrinthA system of communicating sacs and ducts within the bony labyrinth of the inner ear that includes the cochlea and vestibular apparatus. It is filled with endolymph and surrounded by perilymph and bone.
MenarcheThe first menstrual discharge.
Ménière's diseaseDeafness, tinnitus, and vertigo resulting from a disorder of the labyrinth.
MeningesA group of three fibrous membranes covering the central nervous system, composed of the dura mater, arachnoid mater, and pia mater.
MenisciWedge-shaped fibrocartilages in certain synovial joints.
MenopauseThe period marked by the cessation of menstrual periods in the human female.
Menstrual cycleThe rhythmic female reproductive cycle, characterized by changes in hormone levels and physical changes in the uterine lining.
MenstruationThe discharge of blood and tissue from the uterus at the end of the menstrual cycle.
Mesencephalic aqueductThe channel that connects the third and fourth ventricles of the brain; also called the aqueduct of Sylvius.
MesencephalonThe midbrain, which contains the corpora quadrigemina and the cerebral peduncles.
MesenchymeAn embryonic connective tissue that can migrate, and from which all connective tissues arise.
Mesenteric patchesClusters of lymph nodes on the walls of the small intestine; also called Peyer's patches.
MesenteryA fold of peritoneal membrane that attaches an abdominal organ to the abdominal wall.
MesodermThe middle one of the three primary germ layers.
MesotheliumA simple squamous epithelial tissue that lines body cavities and covers visceral organs; also called serosa.
MesovariumThe peritoneal fold that attaches an ovary to the broad ligament of the uterus.
Messenger RNA(mRNA) A type of RNA that contains a base sequence complementary to a part of the DNA that specifies the synthesis of a particular protein.
MetabolismThe sum total of the chemical changes that occur within a cell.
MetacarpusThe region of the hand between the wrist and the phalanges, including the five metacarpal bones that support the palm of the hand.
MetarterioleA small blood vessel that emerges from an arteriole, passes through a capillary network, and empties into a venule.
MetastasisThe spread of a disease from one organ or body part to another.
MetatarsusThe region of the foot between the ankle and the phalanges that includes the five metatarsal bones.
MetencephalonThe most superior portion of the hindbrain that contains the cerebellum and the pons.
MicellesColloidal particles formed by the aggregation of many molecules.
MicrogliaSmall phagocytic cells found in the central nervous system.
MicrovilliMicroscopic hairlike projections of cell membranes on certain epithelial cells.
MicturitionThe process of voiding urine; also called urination.
MidbrainThe portion of the brain between the pons and the forebrain.
Middle earThe middle of the three portions of the ear that contains the three auditory ossicles.
Midsagittal planeA plane that divides the body into equal right and left halves; also called the median plane or mid plane.
MineralocorticoidsSteroid hormones of the adrenal cortex (corticosteroids) that regulate electrolyte balance.
MitochondriaCytoplasmic organelles that serve as sites for the production of most of the cellular energy; the so-called powerhouses of the cell.
MitosisThe process of cell division that results in two identical daughter cells, containing the same number of chromosomes.
Mitral valveThe left atrioventricular heart valve; also called the bicuspid valve.
Mixed nerveA nerve that contains both motor and sensory nerve fibers.
MolalPertaining to the number of moles of solute per kilogram of solvent.
MolarPertaining to the number of moles of solute per litre of solution.
MoleThe number of grams of a chemical that is equal to its formula weight (atomic weight for an element or molecular weight for a compound).
Monoclonal antibodiesIdentical antibodies derived from a clone of genetically identical plasma cells.
MonocyteA phagocytic type of white blood cell, normally constituting about 3% to 8% of the white blood cell count.
MonomerA single molecular unit of a longer, more complex molecule. Monomers are joined together to form dimers, trimers, and polymers; the hydrolysis of polymers eventually yields separate monomers.
MonosaccharideThe monomer of the more complex carbohydrates, examples of which include glucose, fructose, and galactose; also called a simple sugar.
Mons pubisA fatty tissue pad covering the symphysis pubis and covered by pubic hair in the female.
MorulaAn early stage of embryonic development characterized by a solid ball of cells.
MotileCapable of self-propelled movement.
Motor areaA region of the cerebral cortex from which motor impulses to muscles or glands originate.
Motor nerveA nerve composed of motor nerve fibers.
Motor neuronA nerve cell that conducts action potentials away from the central nervous system and innervates effector organs (muscle and glands). It forms the anterior roots of the spinal nerves; also called an efferent neuron.
Motor unitA single motor neuron and the muscle fibers it innervates.
MucosaA mucous membrane that lines cavities and tracts opening to the exterior.
Mucous cellSee goblet cell.
Mucous membraneA thin sheet consisting of layers of visceral organs that include the lining epithelium, submucosal connective tissue, and (in some cases) a thin layer of smooth muscle (the muscularis mucosa).
Multipolar neuronA nerve cell with many processes originating from the cell body.
MuscleA major type of tissue adapted to contract. The three kinds of muscle are cardiac, smooth, and skeletal.
Muscle spindlesSensory organs within skeletal muscles composed of intrafusal fibers. They are sensitive to muscle stretch and provide a length detector within muscles.
MuscularisA muscular layer or tunic of an organ, composed of smooth muscle tissue.
MyelencephalonThe posterior portion of the hindbrain that contains the medulla oblongata.
MyelinA lipoprotein material that forms a sheath-like covering around nerve fibers.
Myelin sheathA sheath surrounding axons formed by successive wrappings of a neuroglial cell membrane. Myelin sheaths are formed by neurolemmocytes in the peripheral nervous system and by oligodendrocytes within the central nervous system.
Myenteric plexusA network of sympathetic and parasympathetic nerve fibers located in the muscularis tunic of the small intestine; also called the plexus of Auerbach.
Myocardial infarctionAn area of necrotic tissue in the myocardium that is filled in by scar (connective) tissue.
MyocardiumThe cardiac muscle layer of the heart.
MyofibrilA bundle of contractile fibers within muscle cells.
MyogenicOriginating within muscle cells; used to describe self-excitation by cardiac and smooth muscle cells.
MyoglobinA molecule composed of globin protein and heme pigment. It is related to hemoglobin but contains only one subunit (instead of the four in hemoglobin) and is found in skeletal and cardiac muscle cells where it serves to store oxygen.
MyogramA recording of electrical activity within a muscle.
MyologyThe science or study of muscle structure and function.
MyometriumThe layer or tunic of smooth muscle within the uterine wall.
Myoneural junctionThe site of contact between an axon of a motor neuron and a muscle fibre.
MyopiaA visual defect in which objects may be seen distinctly only when very close to the eyes; also called nearsightedness.
MyosinA thick myofilament protein that together with actin causes muscle contraction.
MyxedemaA type of edema associated with hypothyroidism. It is characterized by the accumulation of mucoproteins in tissue fluid.
NADNicotinamide adenine dinucleotide; a coenzyme derived from niacin that helps to transport electrons from the Krebs cycle to the electron-transport chain within mitochondria.
NailA hardened, keratinized plate that develops from the epidermis and forms a protective covering on the surface of the distal phalanges of fingers and toes.
NaloxoneA drug that antagonizes the effects of morphine and endorphins.
Nasal cavityA mucosa-lined space above the oral cavity, divided by a nasal septum. It is the first chamber of the respiratory system.
Nasal conchaA scroll-like bone extending medially from the lateral wall of the nasal cavity; also called a turbinate bone.
Nasal septumA bony and cartilaginous partition that separates the nasal cavity into two portions.
NasopharynxThe first or uppermost chamber of the pharynx, positioned posterior to the nasal cavity and extending down to the soft palate.
NatriureticAn agent that promotes the excretion of sodium in the urine. Atrial natriuretic hormone has this effect.
Neck1.Any constricted portion, such as the neck of an organ. 2.The cervical region of the body between the head and thorax.
NecrosisCellular death or tissue death due to disease or trauma.
Negative feedbackA mechanism in the body for maintaining a state of internal constancy, or homeostasis; effectors are activated by changes in the internal environment, and the actions of the effectors serve to counteract these changes and maintain a state of balance.
NeonatalThe stage of life from birth to the end of 4 weeks.
NeoplasmA new, abnormal growth of tissue, as in a tumor.
NephronThe functional unit of the kidney, consisting of a glomerulus, convoluted tubules, and a nephron loop.
NerveA bundle of nerve fibers outside the central nervous system.
NeurilemmaA thin, membranous covering surrounding the myelin sheath of a nerve fibre.
Neurofibril nodeA gap in the myelin sheath of a nerve fibre; also called a node of Ranvier.
NeurogliaSpecialised supportive cells of the central nervous system.
NeurohypophysisThe posterior lobe of the pituitary gland derived from the brain. Its major secretions include antidiuretic hormone (ADH), also called vasopressin, and oxytocin, produced in the hypothalamus.
Neuro lemmocyteA specialized neuroglia cell that surrounds an axon fibre of a peripheral nerve and forms the neurilemmal sheath; also called a Schwann cell.
NeuronThe structural and functional unit of the nervous system, composed of a cell body, dendrites, and an axon; also called a nerve cell.
NeurotransmitterA chemical contained in synaptic vesicles in nerve endings that is released into the synaptic cleft, where it stimulates the production of either excitatory or inhibitory postsynaptic potentials.
NeutronsElectrically neutral particles that exist together with positively charged protons in the nucleus of atoms.
NeutrophilA type of phagocytic white blood cell, normally constituting about 60% to 70% of the white blood cell count.
NexusA bond between members of a group; the type of bonds present in single-unit smooth muscles.
NidationImplantation of the blastocyst into the endometrium of the uterus.
NippleA dark pigmented, rounded projection at the tip of the breast.
NorepinephrineA catecholamine released as a neurotransmitter from postganglionic sympathetic nerve endings and as a hormone (together with epinephrine) from the adrenal medulla.
NotochordA flexible rod of tissue that extends the length of the back of an embryo.
NucleolusA dark-staining area within a cell nucleus; the site where ribosomal RNA is produced.
NucleoplasmThe protoplasmic contents of the nucleus of a cell.
NucleotideThe subunit of DNA and RNA macromolecules. Each nucleotide is composed of a nitrogenous base (adenine, guanine, cytosine, and thymine or uracil); a sugar (deoxyribose or ribose); and a phosphate group.
NucleusA spheroid body within a cell that contains the genetic factors of the cell.
Nucleus pulposusThe soft, pulpy core of an intervertebral disc; a remnant of the notochord.
NystagmusInvoluntary oscillary movements of the eye.
ObeseExcessively fat.
OlfactoryPertaining to the sense of smell.
Olfactory bulbAn aggregation of sensory neurons of an olfactory nerve, lying inferior to the frontal lobe of the cerebrum on either lateral side of the crista galli of the ethmoid bone.
Olfactory tractThe olfactory sensory tract of axons that conveys impulses from the olfactory bulb to the olfactory portion of the cerebral cortex.
OligodendrocyteA type of neuroglial cell concerned with the formation of the myelin of nerve fibers within the central nervous system.
OncologyThe study of tumors.
Oncotic pressureThe colloid osmotic pressure of solutions produced by proteins. In plasma, it serves to counterbalance the outward filtration of fluid from capillaries due to hydrostatic pressure.
OocyteA developing egg cell.
OogenesisThe process of female gamete formation.
OpsonizationThe process by which antibodies enhance the ability of phagocytic cells to attack bacteria.
OpticPertaining to the eye.
Optic chiasmaAn X-shaped structure on the inferior aspect of the brain, anterior to the pituitary gland, where there is a partial crossing over of fibers in the optic nerves; also called the optic chiasm.
Optic disc A small region of the retina where the fibers of the ganglion neurons exit from the eyeball to form the optic nerve; also called the blind spot.
Optic tractA bundle of sensory axons located between the optic chiasma and the thalamus that functions to convey visual impulses from the photoreceptors within the eye.
OralPertaining to the mouth.
Ora serrataThe jagged peripheral margin of the retina.
OrganA structure consisting of two or more tissues that performs a specific function.
OrganelleA minute living structure of a cell with a specific function.
OrganismAn individual living creature.
OrificeAn opening into a body cavity or tube.
OriginThe place of muscle attachment-usually the more stationary point or the proximal bone; opposite the insertion.
OropharynxThe second portion of the pharynx, located posterior to the oral cavity and extending from the soft palate to the hyoid bone.
OsmolalityA measure of the total concentration of a solution; the number of moles of solute per kilogram of solvent.
OsmoreceptorsSensory neurons that respond to changes in the osmotic pressure of the surrounding fluid.
OsmosisThe passage of solvent (water) from a more dilute to a more concentrated solution through a membrane that is more permeable to water than to the solute.
Osmotic pressureA measure of the tendency of a solution to gain water by osmosis when separated by a membrane from pure water. Directly related to the osmolality of the solution, it is the pressure required to just prevent osmosis.
Osseous tissueBone tissue.
OssicleOne of the three bones of the middle ear; also called the auditory ossicle.
OssificationThe process of bone tissue formation.
OsteoblastA bone-forming cell.
OsteoclastA cell that causes erosion and resorption of bone tissue.
OsteocyteA mature bone cell.
OsteologyThe study of the structure and function of bone and the entire skeleton.
OsteomalaciaSoftening of bones due to a deficiency of vitamin D and calcium.
OsteonA group of osteocytes and concentric lamellae surrounding a central canal, constituting the basic unit of structure in osseous tissue; also called a haversian system.
OsteoporosisDemineralization of bone, seen most commonly in postmenopausal women and patients who are inactive or paralyzed. It may be accompanied by pain, loss of stature, and other deformities and fractures.
OtolithsSmall, hardened particles of calcium carbonate in the saccule and utricle of the inner ear, associated with the receptors of equilibrium; also called statoconia.
Outer earThe outer portion of the ear, consisting of the auricle and the external auditory canal.
Oval windowAn oval opening in the bony wall between the middle and inner ear, into which the footplate of the stapes fits; also called the vestibular window.
Ovarian follicleA developing ovum and its surrounding epithelial cells.
Ovarian ligamentA cordlike connective tissue that attaches the ovary to the uterus.
OvaryThe female gonad in which ova and certain sexual hormones are produced.
OviductThe tube that transports ova from the ovary to the uterus; also called the uterine tube or fallopian tube.
OvulationThe rupture of an ovarian (graafian) follicle with the release of an ovum.
OvumA secondary oocyte capable of developing into a new individual when fertilized by a spermatozoon.
Oxidative phosphorylationThe formation of ATP using energy derived from electron transport to oxygen. It occurs in the mitochondria.
Oxidizing agentAn atom that accepts electrons in an oxidation-reduction reaction.
OxyhemoglobinA compound formed by the bonding of molecular oxygen to hemoglobin.
Oxyhemoglobin saturationThe ratio, expressed as a percentage, of the amount of oxyhemoglobin relative to the total amount of hemoglobin in blood.
OxytocinOne of the two hormones produced in the hypothalamus and secreted by the posterior pituitary (the other hormone is vasopressin). Oxytocin stimulates the contraction of uterine smooth muscles and promotes milk ejection in females.
PacemakerA group of cells that has the fastest spontaneous rate of depolarization and contraction in a mass of electrically coupled cells; in the heart, this is the sinoatrial, or SA, node.
PAHPara-aminohippuric acid; a substance used to measure total renal plasma flow because its clearance rate is equal to the total rate of plasma flow to the kidneys. PAH is filtered and secreted but not reabsorbed by the renal nephrons.
PalateThe roof of the oral cavity.
PalatinePertaining to the palate.
PalmarPertaining to the palm of the hand.
PalpebraAn eyelid.
PancreasA mixed organ in the abdominal cavity that secretes pancreatic juices into the GI tract and insulin and glucagon into the blood.
Pancreatic ductA drainage tube that carries pancreatic juice from the pancreas into the duodenum of the hepatopancreatic ampulla.
Pancreatic isletsA cluster of cells within the pancreas that forms the endocrine portion and secretes insulin and glucagon; also called islets of Langerhans.
Papillary muscleMuscular projections from the ventricular walls of the heart to which the chordea tendineae are attached.
Paranasal sinusAn air chamber lined with a mucous membrane that communicates with the nasal cavity.
ParasympatheticPertaining to the division of the autonomic nervous system concerned with activities that, in general, inhibit or oppose the physiological effects of the sympathetic nervous system.
Parathyroid hormone(PTH) A polypeptide hormone secreted by the parathyroid glands. PTH acts to raise the blood Ca++ levels primarily by stimulating reabsorption of bone.
ParathyroidsSmall endocrine glands embedded on the posterior surface of the thyroid glands that are concerned with calcium metabolism.
ParietalPertaining to a wall of an organ or cavity.
Parietal pleuraThe thin serous membrane attached to the thoracic walls of the pleural cavity.
Parkinson's diseaseA tremor of the resting muscles and other symptoms caused by inadequate dopamine-producing neurons in the basal nuclei of the cerebrum; also called paralysis agitans.
Parotid glandOne of the paired salivary glands located on the side of the face over the masseter muscle just anterior to the ear and connected to the oral cavity through a salivary duct.
ParturitionThe process of giving birth; childbirth.
Passive immunitySpecific immunity granted by the administration of antibodies made by another organism.
PathogenAny disease-producing microorganism or substance.
PectoralPertaining to the chest region.
Pectoral girdleThe portion of the skeleton that supports the upper extremities.
PedicleThe portion of a vertebra that connects and attaches the lamina to the body.
PelvicPertaining to the pelvis.
Pelvic girdleThe portion of the skeleton to which the lower extremities are attached.
PelvisA basin like bony structure formed by the sacrum and ossa coxae.
PenisThe male organ of copulation, used to introduce sperm into the female vagina and through which urine passes during urination.
PennatePertaining to a skeletal muscle fiber arrangement in which the fibers are attached to tendinous slips in a featherlike pattern.
PepsinThe protein-digesting enzyme secreted in gastric juice.
Peptic ulcerAn injury to the mucosa of the esophagus, stomach, or small intestine due to the action of acidic gastric juice.
Perforating canalA minute duct through compact bone by which blood vessels and nerves penetrate to the central canal of an osteon; also called Volkmann's canal.
PericardiumA protective serous membrane that surrounds the heart.
PerichondriumA toughened connective sheet that covers some kinds of cartilage.
PerikaryonThe cell body of a neuron.
PerilymphA fluid of the inner ear that provides a liquid-conducting medium for the vibrations involved in hearing and the maintenance of equilibrium.
PerimysiumFascia (connective tissue) surrounding a bundle of muscle fibers.
PerineumThe floor of the pelvis, which is the region between the anus and the symphysis pubis. It is the region that contains the external genitalia.
PerineuriumConnective tissue surrounding a bundle of nerve fibers.
Periodontal membraneA fibrous connective tissue lining the dental alveoli.
PeriosteumA fibrous connective tissue covering the outer surface of bone.
Peripheral nervous systemThe nerves and ganglia of the nervous system that lie outside of the brain and spinal cord; PNS.
PeristalsisRhythmic contractions of smooth muscle in the walls of various tubular organs by which the contents are forced onward.
PeritoneumThe serous membrane that lines the abdominal cavity and covers the abdominal visceral organs. .
pHA measure of the relative acidity or alkalinity of a solution, numerically equal to 7 for neutral solutions. The pH scale in common use ranges from 0 to 14. Solutions with a pH lower than 7 are acidic and those with a higher pH are basic.
PhagocytosisCellular eating; the ability of some cells (such as white blood cells) to engulf large particles (such as bacteria) and digest these particles by merging the food vacuole in which they are contained with a lysosome containing digestive enzymes.
PhalanxA bone of a finger or toe.
PharynxThe organ of the digestive system and respiratory system located at the back of the oral and nasal cavities that extends to the larynx anteriorly and to the esophagus posteriorly; also called the throat.
PhotoreceptorA sensory nerve ending that responds to the stimulation of light.
PhysiologyThe science that deals with the study of body functions.
Pia materThe innermost meninx that is in direct contact with the brain and spinal cord.
Pineal glandA small cone-shaped gland located in the roof of the third ventricle.
PinnaThe outer, fleshy portion of the external ear; also called the auricle.
PinocytosisCell drinking; invagination of the cell membrane forming narrow channels that pinch off into vacuoles. This allows for cellular intake of extracellular fluid and dissolved molecules.
Pituitary glandA small, pea-shaped endocrine gland situated on the interior surface of the diencephalonic region of the brain, consisting of anterior and posterior lobes; also called the hypophysis.
Pivot jointA synovial joint in which the rounded head of one bone articulates with the depressed cup of another to permit a rotational type of movement.
PlacentaThe organ of metabolic exchange between the mother and the fetus.
PlantarPertaining to the sole of the foot.
PlasmaThe fluid, extracellular portion of circulating blood.
Plasma cellsCells derived from B lymphocytes that produce and secrete large amounts of antibodies. They are responsible for humoral immunity.
PlateletsSmall fragments of specific bone marrow cells that function in blood coagulation; also called thrombocytes.
PleuralPertaining to the serous membranes associated with the lungs.
Pleural cavityThe potential space between the visceral pleura and parietal pleura.
Pleural membranesSerous membranes that surround the lungs and provide protection and compartmentalization.
PlexusA network of interlaced nerves or vessels.
Plicae circularesDeep folds within the wall of the small intestine that increase the absorptive surface area.
Pneumotaxic areaThe region of the respiratory control centre located in the pons of the brain.
Polar bodyA small daughter cell formed by meiosis that degenerates in the process of oocyte production.
Polar moleculeA molecule in which the shared electrons are not evenly distributed, so that one side of the molecule is negatively (or positively) charged in comparison with the other side. Polar molecules are soluble in polar solvents, such as water.
PolydipsiaExcessive thirst.
PolymerA large molecule formed by the combination of smaller subunits, or monomers.
Polymorphonuclear leukocyteA granular leukocyte containing a nucleus with a number of lobes connected by thin, cytoplasmic strands. This type includes neutrophils, eosinophils, and basophils.
PolypeptideA chain of amino acids connected by covalent bonds called peptide bonds. A very large polypeptide is called a protein.
PolysaccharideA carbohydrate formed by covalent bonding of numerous monosaccharides. Examples include glycogen and starch.
PolyuriaExcretion of an excessively large volume of urine in a given period.
PonsThe portion of the brain stem just above the medulla oblongata and anterior to the cerebellum.
PoplitealPertaining to the concave region on the posterior aspect of the knee.
PosteriorToward the back; also called dorsal.
Posterior pituitarySee neurohypophysis.
Posterior rootAn aggregation of sensory neuron fibers lying between a spinal nerve and the posterolateral aspect of the spinal cord; also called the dorsal root or sensory root.
Posterior root ganglionA cluster of cell bodies of sensory neurons located along the posterior root of a spinal nerve.
Postganglionic neuronThe second neuron in an autonomic motor pathway. Its cell body is outside the central nervous system and it terminates at an effector organ.
PostnatalAfter birth.
Postsynaptic inhibitionThe inhibition of a postsynaptic neuron by axon endings that release a neurotransmitter that induces hyperpolarization (inhibitory postsynaptic potentials).
Preganglionic neuronThe first neuron in an autonomic motor pathway. Its cell body is inside the central nervous system and it terminates on a postganglionic neuron.
PregnancyA condition in which a female is carrying a developing offspring within the body.
PrenatalPertaining to the period of offspring development during pregnancy; before birth.
PrepuceA fold of loose, retractable skin covering the glans of the penis or clitoris; also called the foreskin.
Presynaptic inhibitionNeural inhibition in which axoaxonic synapses inhibit the release of neurotransmitter chemicals from the presynaptic axon terminal.
ProlactinA hormone secreted by the anterior pituitary that, in conjunction with other hormones, stimulates lactation in the postpartum female. It may also participate (along with the gonadotropins) in regulating gonadal function in some mammals.
PronationA rotational movement of the forearm in which the palm of the hand is turned posteriorly.
ProprioceptorA sensory nerve ending that responds to changes in tension in a muscle or tendon.
ProstaglandinAny of a family of fatty acids that have numerous autocrine regulatory functions, including the stimulation of uterine contractions and of gastric acid secretion and the promotion of inflammation.
ProstateA walnut-shaped gland surrounding the male urethra just below the urinary bladder that secretes an additive to seminal fluid during ejaculation.
ProsthesisAn artificial device to replace a diseased or worn body part.
ProtonA unit of positive charge in the nucleus of atoms.
ProtoplasmA general term for the colloidal complex of protein that constitutes the living material of a cell. It includes cytoplasm and nucleoplasm.
ProtractionThe movement of a body part, such as the mandible, forward on a plane parallel with the ground; the opposite of retraction.
ProximalCloser to the mid-plane of the body or to the origin of an appendage; the opposite of distal.
PseudohermaphroditeAn individual with some of the physical characteristics of both sexes, but who lacks functioning gonads of both sexes; a true hermaphrodite has both testes and ovaries.
PseudopodsFoot-like extensions of the cytoplasm that enable some cells (with amoeboid motion) to move across a substrate. Pseudopods are also used to surround food particles in the process of phagocytosis.
PtyalinAn enzyme in saliva that catalyses the hydrolysis of starch into smaller molecules; also called salivary amylase.
PubertyThe period of development in which the reproductive organs become functional.
PulmonaryPertaining to the lungs.
Pulmonary circulationThe system of blood vessels from the right ventricle of the heart to the lungs that transports deoxygenated blood and returns oxygenated blood from the lungs to the left atrium of the heart.
Pulp cavityA cavity within the centre of a tooth that contains blood vessels, nerves, and lymphatics.
PupilThe opening through the iris that permits light to enter the posterior cavity of the eyeball and be refracted by the lens through the vitreous chamber.
Purkinje fibersSee conduction myofibers.
Pyloric sphincterA modification of the muscularis tunic between the stomach and the duodenum that functions to regulate the food material leaving the stomach.
PyramidAny of several structures that have a pyramidal shape (e.g., the renal pyramids in the kidney and the medullary pyramids on the anterior surface of the brain).
PyrogenA fever-producing substance.
QRS complexThe principal deflection of an electrocardiogram that is produced by depolarization of the ventricles.
RamusA branch of a bone, artery, or nerve.
RapheA ridge or a seam-like structure between two similar parts of a body organ, as in the scrotum.
ReceptorA sense organ or a specialized distal end of a sensory neuron that receives stimuli from the environment.
RectumThe terminal portion of the GI tract, between the sigmoid colon and the anal canal.
Red marrowA tissue that forms blood cells, located in the medullary cavity of certain bones.
Red nucleusAn aggregation of grey matter of a reddish colour located in the upper portion of the midbrain. It sends fibers to certain brain tracts.
Reduced hemoglobinHemoglobin with iron in the reduced ferrous state. It is able to bond with oxygen but is not combined with oxygen. Also called deoxyhemoglobin.
Reducing agentAn electron donor in a coupled oxidation-reduction reaction.
ReflexA rapid involuntary response to a stimulus.
Reflex arcThe basic conduction pathway through the nervous system, consisting of a sensory neuron, an association neuron, and a motor neuron.
Regional anatomyThe division of anatomy concerned with structural arrangement in specific areas of the body, such as the head, neck, thorax, or abdomen.
RenalPertaining to the kidney.
Renal corpuscleThe portion of the nephron consisting of the glomerulus and a glomerular capsule; also called the malpighian corpuscle.
Renal cortexThe outer portion of the kidney, primarily vascular.
Renal medullaThe inner portion of the kidney, including the renal pyramids and renal columns.
Renal pelvisThe inner cavity of the kidney formed by the expanded ureter and into which the calyces open.
Renal plasma clearance rateThe millilitres of plasma cleared of a particular solute per minute by the excretion of that solute in the urine. If there is no reabsorption or secretion of that solute by the nephron tubules, the plasma clearance rate is equal to the glomerular filtration rate.
Renal pyramidA triangular structure within the renal medulla composed of nephron loops and the collecting ducts.
RepolarizationThe reestablishment of the resting membrane potential after depolarization has occurred.
RespirationThe exchange of gases between the external environment and the cells of an organism.
Respiratory acidosisA lowering of the blood pH to below 7.35 due to accumulation of CO2 as a result of hypoventilation.
Respiratory alkalosisA rise in blood pH to above 7.45 due to excessive elimination of blood CO2 as a result of hyperventilation.
Respiratory centreThe structure or portion of the brain stem that regulates the depth and rate of breathing.
Respiratory distress syndromeA lung disease of the newborn, most frequently occurring in premature infants, that is caused by abnormally high alveolar surface tension as a result of a deficiency in lung surfactant; also called hyaline membrane disease.
Respiratory membraneA thin, moistened membrane within the lungs, composed of an alveolar portion and a capillary portion, through which gaseous exchange occurs.
Rete testisA network of ducts in the centre of the testis associated with the production of spermatozoa.
Reticular formationA network of nervous tissue fibers in the brain stem that arouses the higher brain centres.
RetinaThe principal portion of the internal tunic of the eyeball that contains the photoreceptors.
RetractionThe movement of a body part, such as the mandible, backward on a plane parallel with the ground; the opposite of protraction.
RetroperitonealPositioned behind the parietal peritoneum.
RhodopsinA pigment in rod cells that undergoes a photochemical dissociation in response to light and in so doing stimulates electrical activity in the photoreceptors.
Rhythmicity areaA portion of the respiratory control centre located in the medulla oblongata that controls inspiratory and expiratory phases.
RibosomeA cytoplasmic organelle composed of protein and RNA in which protein synthesis occurs.
RicketsA condition caused by a deficiency of vitamin D and associated with an interference of the normal ossification of bone.
Right lymphatic ductA major vessel of the lymphatic system that drains lymph from the upper right portion of the body into the right subclavian vein.
Rigor mortisThe stiffening of a dead body due to the depletion of ATP and the production of rigor complexes between actin and myosin in muscles.
RNARibonucleic acid; a nucleic acid consisting of the nitrogenous bases adenine, guanine, cytosine, and uracil; the sugar ribose; and phosphate groups. There are three types of RNA found in cytoplasm: messenger RNA (mRNA), transfer RNA (tRNA) and ribosomal RNA (rRNA).
RodA photoreceptor in the retina of the eye that is specialized for colourless, dim-light vision.
Root canalThe hollow, tubular extension of the pulp cavity into the root of the tooth that contains vessels and nerves.
RotationThe movement of a bone around its own longitudinal axis.
Round windowA round, membrane-covered opening between the middle and inner ear, directly below the oval window; also called the cochlear window.
RugaeThe folds or ridges of the mucosa of an organ.
Saccadic eye movementsVery rapid eye movements that occur constantly and that change the focus on the retina from one point to another.
SacculeA saclike cavity in the membranous labyrinth inside the vestibule of the inner ear that contains a vestibular organ for equilibrium.
SacralPertaining to the sacrum.
Sacral plexusA network of nerve fibers that arises from spinal nerves L4 through S3. Nerves arising from the sacral plexus merge with those from the lumbar plexus to form the lumbosacral plexus and supply the lower extremity.
Saddle jointA synovial joint in which the articular surfaces of both bones are concave in one plane and convex or saddle shaped, in the other plane, such as in the distal carpometacarpal joint of the thumb.
Sagittal planeA vertical plane, running parallel to the midsagittal plane, that divides the body into unequal right and left portions.
Salivary glandAn accessory digestive gland that secretes saliva into the oral cavity.
Saltatory conductionThe rapid passage of action potentials from one node of Ranvier (neurofibril node) to another in myelinated axons.
SarcolemmaThe cell membrane of a muscle fiber.
SarcomereThe portion of a striated muscle fiber between the two adjacent Z lines that is considered the functional unit of a myofibril.
SacroplasmThe cytoplasm within a muscle fiber.
Sarcoplasmic reticulumThe smooth or agranular endoplasmic reticulum of skeletal muscle cells. It surrounds each myofibril and stores Ca++ when the muscle is at rest.
Scala tympaniThe lower channel of the cochlea that is filled with perilymph.
Scala vestibuliThe upper channel of the cochlea that is filled with perilymph.
ScleraThe outer white layer of fibrous connective tissue that forms the protective covering of the eyeball.
Scleral venous sinusA circular venous drainage for the aqueous humor from the anterior chamber; located at the junction of the sclera and the cornea; also called the canal of Schlemm.
ScrotumA pouch of skin that contains the testes and their accessory organs.
Sebaceous glandAn exocrine gland of the skin that secretes sebum.
SebumAn oily, waterproofing secretion of the sebaceous glands.
Second messengerA molecule or ion whose concentration within a target cell is increased by the action of a regulatory compound (e.g., a hormone or neurotransmitter) and which stimulates the metabolism of that target cell in a way that mediates the intracellular effects of that regulatory compound.
SecretinA polypeptide hormone secreted by the small intestine in response to acidity of the intestinal lumen. Along with cholecystokinin, secretin stimulates the secretion of pancreatic juice into the small intestine.
SemenThe thick, whitish secretion of the reproductive organs of the male, consisting of spermatozoa and additives from the prostate and seminal vesicles.
Semicircular canalsTubule channels within the inner ear that contain receptors for equilibrium.
Semilunar valveCrescent- or half-moon-shaped heart valves positioned at the entrances to the aorta and the pulmonary trunk.
Seminal vesiclesA pair of accessory male reproductive organs lying posterior and inferior to the urinary bladder that secrete additives to spermatozoa into the ejaculatory ducts.
Seminiferous tubulesNumerous small ducts in the testes, where spermatozoa are produced.
Semipermeable membraneA membrane with pores of a size that permits the passage of solvent and some solute molecules while restricting the passage of other solute molecules.
SenescenceThe process of aging.
Sensory areaA region of the cerebral cortex that receives and interprets sensory nerve impulses.
Sensory neuronA nerve cell that conducts an impulse from a receptor organ to the central nervous system; also called an afferent neuron.
SeptumA membranous or fleshy wall dividing two cavities.
Serous membraneAn epithelial and connective tissue membrane that lines body cavities and covers visceral organs within these cavities; also called serosa.
Sertoli cellsSee sustentacular cells.
SerumBlood plasma with the clotting elements removed.
Sesamoid boneA membranous bone formed in a tendon in response to joint stress (e.g., the patella).
Sex chromosomesThe X and Y chromosomes; the unequal pairs of chromosomes involved in sex determination (which is based on the presence or absence of a Y chromosome). Females lack a Y chromosome and normally have the genotype XX; males have a Y chromosome and normally have the genotype XY.
ShockAs it relates to the cardiovascular system, this term refers to a rapid, uncontrolled fall in blood pressure, which in some cases becomes irreversible and leads to death.
ShoulderThe region of the body where the humerus articulates with the scapula.
Sickle-cell anemiaA hereditary, autosomal recessive trait that occurs primarily in people of African ancestry, in which it evolved apparently as a protection (in the carrier state) against malaria. In the homozygous state, hemoglobin S is made instead of hemoglobin A; this leads to the characteristic sickling of red blood cells, hemolytic anemia, and organ damage.
Sigmoid colonThe S-shaped portion of the large intestine between the descending colon and the rectum.
Sinoatrial nodeA mass of specialized cardiac tissue in the wall of the right atrium that initiates the cardiac cycle; the SA node; also called the pacemaker.
SinusA cavity or hollow space within a body organ, such as a bone.
SinusoidA small, blood-filled space in certain organs, such as the spleen or liver.
Skeletal muscleA specialized type of multinucleated muscle tissue that occurs in bundles, has cross bands of proteins, and contracts in either a voluntary or involuntary fashion.
Sleep apneaA temporary cessation of breathing during sleep, usually lasting for several seconds.
Sliding filament theoryThe theory that the thick and thin filaments of a myofibril slide past each other during muscle contraction, while maintaining their initial length.
Small intestineThe portion of the GI tract between the stomach and the cecum whose function is the absorption of food nutrients.
Smooth muscleA specialized type of nonstriated muscle tissue composed of fusiform, single-nucleated fibers. It contracts in an involuntary, rhythmic fashion within the walls of visceral organs.
Sodium/potassium pumpAn active transport carrier with ATPase enzymatic activity that acts to accumulate K+ within cells and extrude Na+ from cells, thus maintaining gradients for these ions across the cell membrane.
Soft palateThe fleshy, posterior portion of the roof of the mouth, from the palatine bones to the uvula.
SomaticPertaining to the nonvisceral parts of the body.
SomatomedinsA group of small polypeptides believed to be produced in the liver in response to growth hormone stimulation and to mediate the actions of growth hormone on the skeleton and other tissues.
SomatostatinA polypeptide produced in the hypothalamus that acts to inhibit the secretion of growth hormone from the anterior pituitary. Somatostatin is also produced in the pancreatic islets, but its function there has not been established.
Somatotropic hormoneGrowth hormone; an anabolic hormone secreted by the anterior pituitary that stimulates skeletal growth and protein synthesis in many organs.
Sounds of Korotkoff The sounds heard when pressure measurements are taken. These sounds are produced by the turbulent flow of blood through an artery that has been partially constricted by a pressure cuff.
Spermatic cordThe structure of the male reproductive system composed of the ductus deferens, spermatic vessels, nerves, cremaster muscle, and connective tissue. The spermatic cord extends from a testis to the inguinal ring.
SpermatogenesisThe production of male sex gametes, or spermatozoa.
SpermatozoonA mature male sperm cell, or gamete.
SpermiogenesisThe maturational changes that transform spermatids into spermatozoa.
SphincterA circular muscle that functions to constrict a body opening or the lumen of a tubular structure.
Sphincter of ampullaThe muscular constriction at the opening of the common bile and pancreatic ducts; also called the sphincter of Oddi.
Sphincter of OddiSee sphincter of ampulla.
SphygmomanometerA manometer (pressure transducer) used to measure the blood pressure.
Spinal cordThe portion of the central nervous system that extends downward from the brain stem through the vertebral canal.
Spinal ganglionA cluster of nerve cell bodies on the posterior root of a spinal nerve.
Spinal nerveOne of the 31 pairs of nerves that arise from the spinal cord.
Spindle fibersFilaments that extend from the poles of a cell to its equator and attach to the chromosomes during the metaphase stage of cell division. Contraction of the spindle fibers pulls the chromosomes to opposite poles of the cell.
Spinous processA sharp projection of bone or a ridge of bone, such as on the scapula.
Spiral organThe functional unit of hearing, consisting of a basilar membrane supporting receptor hair cells and a tectorial membrane within the endolymph of the cochlear duct; also known as the organ of Corti.
SpironolactonesDiuretic drugs that act as an aldosterone antagonist.
SpleenA large, blood-filled, glandular organ located in the upper left quadrant of the abdomen and attached by mesenteries to the stomach.
Spongy boneBone tissue with a lattice like structure; also called cancellous bone.
SquamousFlat or scalelike.
StapesThe innermost of the auditory ossicles that fits against the oval window of the inner ear; also called the stirrup.
SteroidA lipid, derived from cholesterol, that has three 6-sided carbon rings and one 5-sided carbon ring. These form the steroid hormones of the adrenal cortex and gonads.
StomachA pouchlike digestive organ located between the esophagus and the duodenum.
StratifiedArranged in layers, or strata.
Stratum basaleThe deepest epidermal layer, where mitotic activity occurs.
Stratum corneumThe outer, cornified layer of the epidermis of the skin.
Stroke volumeThe amount of blood ejected from each ventricle at each heartbeat.
StromaA connective tissue framework in an organ, gland, or other tissue.
Subarachnoid spaceThe space within the meninges between the arachnoid mater and pia mater, where cerebrospinal fluid flows.
Sublingual glandOne of the three pairs of salivary glands. It is located below the tongue and its duct opens to the side of the lingual frenulum.
Submandibular glandOne of the three pairs of salivary glands. It is located below the mandible and its duct opens to the side of the lingual frenulum.
SubmucosaA layer of supportive connective tissue that underlies a mucous membrane.
Submucosal plexusA network of sympathetic and parasympathetic nerve fibers located in the submucosa tunic of the small intestine; also called the plexus of Meissner.
SubstrateIn enzymatic reactions, the molecules that combine with the amino acids lining the active sites of an enzyme and are converted to products by catalysis of the enzyme.
SulcusA shallow impression or groove.
SuperficialToward or near the surface.
Superficial fasciaA binding layer of connective tissue between the dermis of the skin and the underlying muscle.
SuperiorToward the upper part of a structure or toward the head; also called cephalic.
Superior vena cavaA large systemic vein that collects blood from regions of the body superior to the heart and returns it to the right atrium.
SupinationRotation of the arm so that the palm is directed forward or anteriorly; the opposite of pronation.
Suppressor T cellA subpopulation of T lymphocytes that acts to inhibit the production of antibodies against specific antigens by B lymphocytes.
Surface anatomyThe division of anatomy concerned with the structures that can be identified from the outside of the body.
SurfactantA substance produced by the lungs that decreases the surface tension within the alveoli.
Suspensory ligament1.A portion of the peritoneum that extends laterally from the surface of the ovary to the wall of the pelvic cavity. 877 2.A ligament that supports an organ or body part, such as that supporting the lens of the eye.
Sustentacular cellsSpecialized cells within the testes that supply nutrients to developing spermatozoa; also called Sertoli cells or nurse cells.
Sutural boneA small bone positioned within a suture of certain cranial bones; also called a wormian bone.
SutureA type of fibrous joint found between bones of the skull.
Sweat glandA skin gland that secretes a fluid substance for evaporative cooling.
SympatheticPertaining to the division of the autonomic nervous system concerned with activities that, in general, arouse the body for physical activity; also called the thoracolumbar division.
SymphysisA type of cartilaginous joint characterized by a fibrocartilaginous pad between the articulating bones, which provides slight movement.
Symphysis pubisA slightly movable joint located anteriorly between the two pubic bones of the pelvic girdle.
SynapseA minute space between the axon terminal of a presynaptic neuron and a dendrite of a postsynaptic neuron.
SynarthrosisA fibrous joint, such as a syndesmosis or a suture.
SynchondrosisA cartilaginous joint in which the articulating bones are separated by hyaline cartilage.
SyndesmosisA type of fibrous joint in which two bones are united by an interosseous ligament.
SynergistA muscle that assists the action of the prime mover.
SynergisticPertaining to regulatory processes or molecules (such as hormones) that have complementary or additive effects.
Synovial cavityA space between the two bones of a synovial joint, filled with synovial fluid.
Synovial jointA freely movable joint in which there is a synovial cavity between the articulating bones; also called a diarthrotic joint.
Synovial membraneThe inner membrane of a synovial capsule that secretes synovial fluid into the joint cavity.
SystemA group of body organs that function together.
SystemicRelating to the entire organism rather than to individual parts.
Systemic anatomyThe division of anatomy concerned with the structure and function of the various systems.
Systemic circulation The portion of the circulatory system concerned with blood flow from the left ventricle of the heart to the entire body and back to the heart via the right atrium (in contrast to the pulmonary system, which involves the lungs).
SystoleThe muscular contraction of a heart chamber during the cardiac cycle.
Systolic pressureArterial blood pressure during the ventricular systolic phase of the cardiac cycle.
TachycardiaAn excessively rapid heart rate, usually in excess of 100 beats per minute (in contrast to bradycardia, in which the heart rate is very slow).
TactilePertaining to the sense of touch.
Taeniae coliThe three longitudinal bands of muscle in the wall of the large intestine.
Target organThe specific body organ that a particular hormone affects.
Tarsal glandAn oil-secreting gland that opens on the exposed edge of each eyelid; also called a meibomian gland.
TarsusThe region of the foot containing the seven tarsal bones.
Taste budAn organ containing the chemocreceptors associated with the sense of taste.
T cellA type of lymphocyte that provides cell-mediated immunity (in contrast to B lymphocytes, which provide humoral immunity through the secretion of antibodies). There are three subpopulations of T cells cytotoxic, helper, and suppressor.
Tectorial membraneA gelatinous membrane positioned over the hair cells of the spiral organ in the cochlea.
TelencephalonThe anterior portion of the forebrain, constituting the cerebral hemispheres and related parts.
Tendo calcaneousThe tendon that attaches the calf muscles to the calcaneous bone; also called the Achilles tendon.
TendonA band of dense regular connective tissue that attaches muscle to bone.
Tendon sheathA covering of synovial membrane surrounding certain tendons.
Tentorium cerebelliAn extension of dura mater that forms a partition between the cerebral hemispheres and the cerebellum and covers the cerebellum.
TeratogenAny agent or factor that causes a physical defect in a developing embryo or fetus.
TestisThe primary reproductive organ of a male that produces spermatozoa and male sex hormones.
TestosteroneThe major androgenic steroid secreted by the interstitial cells of the testes after puberty.
TetanusA smooth contraction of a muscle (as opposed to muscle twitching).
ThalamusAn oval mass of grey matter within the diencephalon that serves as a sensory relay centre.
ThalassemiaAny of a group of hemolytic anemias caused by the hereditary inability to produce either the alpha or beta chain of hemoglobin. It is found primarily among Mediterranean people.
ThighThe proximal portion of the lower extremity between the hip and the knee in which the femur is located.
Third ventricleA narrow cavity between the right and left halves of the thalamus and between the lateral ventricles that contains cerebrospinal fluid.
ThoracicPertaining to the chest region.
Thoracic ductThe major lymphatic vessel of the body that drains lymph from the entire body, except for the upper right quadrant, and returns it to the left subclavian vein.
ThoraxThe chest.
Threshold stimulusThe weakest stimulus capable of producing an action potential in an excitable cell.
ThrombocyteA blood platelet formed from a fragmented megakaryocyte.
ThrombusA blood clot produced by the formation of fibrin threads around a platelet plug.
ThymusA bilobed lymphoid organ positioned in the upper mediastinum, posterior to the sternum and between the lungs.
Thyroid cartilageThe largest cartilage in the larynx that supports and protects the vocal cords; commonly called the Adam's apple.
ThyroxineAlso called tetraiodothyronine, or T4. The major hormone secreted by the thyroid gland, which regulates the basal metabolic rate and stimulates protein synthesis in many organs. A deficiency of this hormone in early childhood produces cretinism.
TinnitusThe spontaneous sensation of a ringing sound or other noise without sound stimuli.
TissueAn aggregation of similar cells and their binding intercellular substance, joined to perform a specific function.
TongueA protrusible muscular organ on the floor of the oral cavity.
TonsilA node of lymphoid tissue located in the mucous membrane of the pharynx.
ToxinA poison.
TrabeculaeA supporting framework of fibers crossing the substance of a structure, as in the lamellae of spongy bone.
TracheaThe airway leading from the larynx to the bronchi composed of cartilaginous rings and a ciliated mucosal lining of the lumen; commonly called the windpipe.
TractA bundle of nerve fibers within the central nervous system.
Transverse colonA portion of the large intestine that extends from right to left across the abdomen between the hepatic and splenic flexures.
Transverse fissureThe prominent cleft that horizontally separates the cerebrum from the cerebellum.
Transverse planeA plane that divides the body into superior and inferior portions; also called a horizontal, or cross-sectional, plane.
Tricuspid valveThe heart valve located between the right atrium and the right ventricle.
TrigoneA triangular area in the urinary bladder between the openings of the ureters and the urethra.
TriiodothyronineAbbreviated T3; a hormone secreted in small amounts by the thyroid; the active hormone in target cells, formed from thyroxine.
TrochanterA broad, prominent process on the proximolateral portion of the femur.
TrochleaA pulley-like anatomical structure (e.g., the medial surface of the distal end of the humerus that articulates with the ulna).
True vocal cordsFolds of the mucous membrane in the larynx that produce sound as they are pulled taut and vibrated.
TrunkThe thorax and abdomen together.
TrypsinA protein-digesting enzyme in pancreatic juice that is released into the small intestine.
TubercleA small, elevated process on a bone.
TuberosityAn elevation or protuberance on a bone.
Tunica albugineaA tough, fibrous tissue surrounding the testis.
Tympanic membraneThe membranous eardrum positioned between the external and middle ear.
Umbilical cordA cordlike structure containing the umbilical arteries and vein and connecting the fetus with the placenta.
UmbilicusThe site where the umbilical cord was attached to the fetus; commonly called the navel.
Unipolar neuronA nerve cell that has a single nerve fiber extending from its cell body.
Universal donorA person with blood type O who is able to donate blood to people with other blood types in emergency blood transfusions.
Universal recipientA person with blood type AB who can receive blood of any type in emergency transfusions.
Upper extremityThe appendage attached to the pectoral girdle, consisting of the shoulder, brachium, elbow, antebrachium, and hand.
UreaThe chief nitrogenous waste product of protein catabolism in the urine, formed in the liver from amino acids.
UremiaThe retention of urea and other products of protein catabolism as a result of inadequate kidney function.
UreterA tube that transports urine from the kidney to the urinary bladder.
UrethraA tube that transports urine from the urinary bladder to the outside of the body.
Urinary bladderA distensible sac that stores urine, situated in the pelvic cavity posterior to the symphysis pubis.
UrobilinogenA compound formed from bilirubin in the small intestine; some is excreted in the feces, and some is absorbed and enters the enterohepatic circulation, where it may be excreted either in the bile or in the urine.
Uterine tubeThe tube through which the ovum is transported to the uterus and the site of fertilization; also called the oviduct or fallopian tube.
UterusA hollow, muscular organ in which a fetus develops. It is located within the female pelvis between the urinary bladder and the rectum; commonly called the womb.
UtricleAn enlarged portion of the membranous labyrinth, located within the vestibule of the inner ear.
UvulaA fleshy, pendulous portion of the soft palate that blocks the nasopharynx during swallowing.
VacuoleA small space or cavity within the cytoplasm of a cell.
VaginaA tubular organ leading from the uterus to the vestibule of the female reproductive tract that receives the male penis during coitus.
Vallate papillaeThe largest papillae on the surface of the tongue. They are arranged in an inverted V-shaped pattern at the posterior portion of the tongue.
VasectomySurgical removal of portions of the ductus deferentia to induce infertility.
VasoconstrictionNarrowing of the lumen of blood vessels due to contraction of the smooth muscles in their walls.
VasodilationWidening of the lumen of blood vessels due to relaxation of the smooth muscles in their walls.
Vasomotor centreA cluster of nerve cell bodies in the medulla oblongata that controls the diameter of blood vessels. It is therefore important in regulating blood pressure.
VeinA blood vessel that conveys blood toward the heart.
Vena cavaOne of two large vessels that return deoxygenated blood to the right atrium of the heart.
VentilationBreathing; the process of moving air into and out of the lungs.
VentralToward the front or facing surface; the opposite of dorsal; also called inferior.
VentricleA cavity within an organ; especially those cavities in the brain that contain cerebrospinal fluid and those in the heart that contain blood to be pumped from the heart.
VenuleA small vessel that carries venous blood from capillaries to a vein.
VermisThe coiled middle lobular structure that separates the two cerebellar hemispheres.
Vertebral canalThe tubelike cavity extending through the vertebral column that contains the spinal cord; also called the spinal canal.
VertigoA feeling of movement or loss of equilibrium.
Vestibular windowSee oval window.
VestibuleA space or cavity at the entrance to a canal, especially that of the nose, inner ear, or vagina.
VillusA minute projection that extends outward into the lumen from the mucosal layer of the small intestine.
VirulentPathogenic; able to cause disease.
VisceraThe organs within the abdominal or thoracic cavities.
VisceralPertaining to the membranous covering of the viscera.
Visceral peritoneumA serous membrane that covers the surfaces of abdominal viscera.
Visceral pleuraA serous membrane that covers the surfaces of the lungs.
VisceroceptorA sensory receptor located within body organs that respond to information concerning the internal environment.
Vitreous humorThe transparent gel that occupies the space between the lens and retina of the eyeball.
VulvaThe external genitalia of the female that surround the opening of the vagina.
White matterBundles of myelinated axons located in the central nervous system.
Yellow marrowSpecialised lipid storage tissue within bone cavities.
ZygoteA fertilized egg cell formed by the union of a sperm cell and an ovum.
ZymogensInactive enzymes that becomes active when part of their structure is removed by the action of another enzyme or by some other means

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